Trinatriumtetraoxovanadat

Gefahreninformationscode (GHS)

• Bildanzeige (GHS)

  

• Alarmwort

  Warnung

• Gefahrenhinweise

  H315：Verursacht Hautreizungen.

  H319：Verursacht schwere Augenreizung.

• Sicherheit

  P261：Einatmen von Staub vermeiden.

  P280：Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.

  P301+P312：BEI VERSCHLUCKEN: Bei Unwohlsein GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen.

  P305+P351+P338：BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen.

Sodium orthovanadate Chemische Eigenschaften,Einsatz,Produktion Methoden

• R-Sätze Betriebsanweisung:

  R20/21/22:Gesundheitsschädlich beim Einatmen,Verschlucken und Berührung mit der Haut.

• S-Sätze Betriebsanweisung:

  S22:Staub nicht einatmen.
  S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.

• Chemische Eigenschaften

  It forms colourless hexagonal columnar crystals that are soluble in water but insoluble in ethanol.

• Verwenden

  Sodium Orthovanadate is an inhibitor of several phosphatases and kinases. General inhibitor of tyrosine phosphatases, a large family of enzymes that catalyze the removal of phosphate groups from tyrosine residues.

• Verwenden

  Sodium orthovanadate (Na3VO4) can be used as a metal precursor in the synthesis of:
  Vanadium-MCM-48 (V-MCM-48) by anion-exchange method. V-MCM-48 is used as a catalyst in oxidation of styrene to benzaldehyde.
  Nanorods of vanadium oxide particles by glycothermal method.
  Yttrium vanadate (YVO4) doped with colloidal europium.

• Definition

  ChEBI: Trisodium vanadate is an inorganic sodium salt of formula Na3VO4 containing the tetrahedral VO4(3-) It has a role as an EC 3.1.3.48 (protein-tyrosine-phosphatase) inhibitor, a radiation protective agent, an apoptosis inducer and an antineoplastic agent. It contains a vanadate(3-).

• synthetische

  Sodium orthovanadate is produced by dissolving vanadium(V) oxide in a solution of sodium hydroxide:
  V2O5 + 6 NaOH → 2 Na3VO4 + 3 H2O
  The salt features tetrahedral VO3-4 anion centers linked to octahedral Na+ cation sites.

• Hazard

  Poison by ingestion.

• Biologische Aktivität

  Inhibitor of protein tyrosine phosphatases, alkaline phosphatases and ATPases.

• Biochem/physiol Actions

  Sodium orthovandate suppresses the activation of p53-mediated apoptosis triggered in response to radiation. It reduces the detrimental effects of hematopoietic syndrome, hematopoiesis and delayed genotoxic effects of induced by total body irradiation of mice.24 In combination with menadione, orthovandate prevents the migration of detached human glioma cells in response to anti-cancer drugs.25

• Sicherheitsprofil

  Poison by ingestion, intraperitoneal, intravenous, and subcutaneous routes. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits toxic fumes of VOx and NazO. See also VANADIUM COMPOUNDS.

• Lager

  Store at RT

Sodium orthovanadate Upstream-Materialien And Downstream Produkte

Trinatriumtetraoxovanadat Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global(256)Suppliers

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