Mipafox
Bezeichnung:Mipafox
CAS-Nr371-86-8
Englisch Name:N,N′-Diisoprophyl phosphordiamide fluoride
CBNumberCB5851771
SummenformelC6H16FN2OP
Molgewicht182.18
MOL-Datei371-86-8.mol
Synonyma
Mipafox
Mipafox physikalisch-chemischer Eigenschaften
Schmelzpunkt | 65° |
Siedepunkt | 125.5°C |
Dichte | 1.2 g/cm3(Temp: 25 °C) |
pka | -2.71±0.70(Predicted) |
Aggregatzustand | solid |
Wasserlöslichkeit | 74.07g/L(temperature not stated) |
EPA chemische Informationen | Mipafox (371-86-8) |
Kennzeichnung gefährlicher | T+ |
R-Sätze: | 39/26/27/28 |
S-Sätze: | 13-45 |
RIDADR | 2783 |
HazardClass | 6.1(b) |
PackingGroup | III |
Giftige Stoffe Daten | 371-86-8(Hazardous Substances Data) |
Toxizität | Formerly used as a systemic insecticide. Its use was discontinued because of severe delayed neuropathy hazard in humans. The oral LD50/LC50 in rabbits is 100 mg/kg. Toxic action is as a neurotoxicant with both acute and delayed actions, acting as a cholinesterase inhibitor (acute toxicity) and as a neurotoxic esterase inhibitor (possibly linked to delayed toxicity). Symptoms in humans are typical anticholinesterase symptoms. Therapy is supportive as well as atropine sulfate and 2-PAM. |