URIDINE 5'-DIPHOSPHORIC ACID SODIUM SALT

Gefahreninformationscode (GHS)

• Bildanzeige (GHS)

  

• Alarmwort

  Warnung

• Gefahrenhinweise

  H371：Kann die Organe schädigen.

URIDINE 5'-DIPHOSPHORIC ACID SODIUM SALT Chemische Eigenschaften,Einsatz,Produktion Methoden

• R-Sätze Betriebsanweisung:

  R22:Gesundheitsschädlich beim Verschlucken.
  R68/22:Gesundheitsschädlich: Möglichkeit irreversiblen Schadens durch Verschlucken.

• Beschreibung

  Uridine-5'-diphosphate disodium salt is a potent, selective P2Y6 receptor native agonist (EC50=300 nM; pEC50=6.52 for human P2Y6 receptor). Uridine-5'-diphosphate disodium salt, an endogenous metabolite, catalyzes the glucuronidation of a wide array of substrates and is used in nucleic acid (RNA) biosynthesis.

• Verwenden

  Uridine 5''-Diphosphate Sodium Salt is a potentially useful P2Y receptor agonist. It can be used in biological study and use in chemical screening methods to identify ligands that promote protein stability, protein crystallization, and structure determination.

• Verwenden

  A phosphorylated derivative of the nucleoside Uridine. It is further phosphorylated by nucleoside diphosphokinase to form the triphosphate analogue.

• Biochem/physiol Actions

  P2Y receptor agonist.

• in vitro

  Uridine-5'-diphosphate disodium salt (100 μM; for 15 min) significantly induces microglial CCL2 and CCL3 mRNA expression.

URIDINE 5'-DIPHOSPHORIC ACID SODIUM SALT Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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