Uridin-5'-(dinatriumdihydrogentriphosphat)

Bezeichnung:Uridin-5'-(dinatriumdihydrogentriphosphat)

CAS-Nr19817-92-6

Englisch Name:Uridine-5'-triphosphoric acid trisodium salt

CBNumberCB8853286

SummenformelC9H16N2NaO15P3

Molgewicht508.14

MOL-Datei19817-92-6.mol

Synonyma

Uridin-5'-(dinatriumdihydrogentriphosphat)

Uridin-5'-(dinatriumdihydrogentriphosphat) physikalisch-chemischer Eigenschaften

Schmelzpunkt	140 °C
Flammpunkt	113 °C
storage temp.	Inert atmosphere,Store in freezer, under -20°C
Löslichkeit	H2O: soluble25 mg of UTP in 0.5 ml of solvent, clear, colorless
Aggregatzustand	Powder
Farbe	White
Wasserlöslichkeit	75 g/100 mL (20 ºC)
BRN	3585234
InChIKey	IKVGSWYKOMJBSB-RFFBCSJBNA-N
SMILES	O[C@@H]1[C@@H]([C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]1N1C=CC(=O)NC1=O)O.[NaH] \|&1:1,2,3,19,r\|
CAS Datenbank	19817-92-6(CAS DataBase Reference)

Sicherheit

Kennzeichnung gefährlicher	Xn,Xi
R-Sätze:	20/21/22-68/20/21/22-68-36/37/38
S-Sätze:	22-26-36-36/37-24/25
WGK Germany	1
RTECS-Nr.	YU8083000
HS Code	29349990

Gefahreninformationscode (GHS)

Uridine-5'-triphosphoric acid trisodium salt Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R20/21/22:Gesundheitsschädlich beim Einatmen,Verschlucken und Berührung mit der Haut.
R68/20/21/22:Gesundheitsschädlich: Möglichkeit irreversiblen Schadens durch Einatmen,Berührung mit der Haut und durch Verschlucken.
R68:Irreversibler Schaden möglich.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S22:Staub nicht einatmen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Beschreibung
Uridine-5'-triphosphoric acid trisodium salt, also known as UTP, is a polyphosphate analogue of uridine that is used in the synthesis of agonists at the G-protein-coupled P2Y receptors.
Chemische Eigenschaften
White crystalline powder
Verwenden
Uridine-5'-triphosphoric acid trisodium salt is a polyphosphate analogue of the nucleoside uridine used in the preparation of potent and selective agonists at the G-protein-coupled P2Y receptors.
Verwenden
P2Y receptor agonist.
Verwenden
psychostimulant
Application
Uridine-5'-triphosphoric acid trisodium salt solution can be used to increase intracellular Ca2+ levels in rat primary tracheal epithelial cells. It is also used as a nucleotide substrate to analyze the activity of MutT homolog 1 (MTH1).
Biochem/physiol Actions
Uridine-5′-Triphosphate?(UTP) is a cytosolic nucleotide component of nucleic acids. It serves as a signaling molecule in the extracellular space. Uridine-5′-Triphosphate?(UTP) is involved in various pathophysiological responses in the nervous system.?UTP also plays a major role in the regeneration process.
in vitro
Uridine triphosphate (UTP) (0, 10, 100, 250, 500, and 1000 μM; 2, 4, 6, 8, 10, and 12 h) trisodium salt enhances RT4-D6P2T cells migration and wound repair. Uridine triphosphate trisodium salt induces Schwannoma cell migration through the activation of P2Y2 receptors and the increase of extracellular MMP-2 activation and expression. Uridine triphosphate (UTP) trisodium salt (Uridine-5'-triphosphoric acid trisodium salt) evokes MAPK phosphorylation in a biphasic pattern MAPK phosphorylation, with an early transient phosphorylation 5 min after treatment and a late and sustained phosphorylation that appeared at 6 h and lasted up to 24 h.

Uridine-5'-triphosphoric acid trisodium salt Upstream-Materialien And Downstream Produkte

Uridin-5'-(dinatriumdihydrogentriphosphat) Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

19817-92-6, Uridine-5'-triphosphoric acid trisodium salt Verwandte Suche:

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