Altizid

Althiazide Chemische Eigenschaften,Einsatz,Produktion Methoden

• Beschreibung

  Althiazide, also known as altizide, is an agent belonging to the class of thiazide diuretics with antihypertensive activity. This aldosterone antagonist is often combined with spironolactone.

• Chemische Eigenschaften

  White Solid

• Originator

  Althiazide,Solchem

• Verwenden

  Diuretic and antihypertensive.

• Definition

  ChEBI: Althiazide is a benzothiadiazine. It is the thiazide and sulfonamide derivative.

• Manufacturing Process

  To 6.75 g (0.0225 mole) of 4-amino-2-chloro-5-(methylsulfamyl) benzenesulfonamide in 45 ml of dimethylformamide is added 4.86 g (0.03 mole) of dimethyl allylmercaptoacetal followed by 1.5 ml ethyl acetate saturated with hydrogen chloride gas. The solution is refluxed for 1.5 hours, cooled and added dropwise with stirring to ice/water. The resulting precipitate is filtered, dried and recrystallized from isopropanol. The recrystallization gave 4.0 g of 2-methyl-3-allylthiomethyl-6-chloro-7-sulfamyl-3,4-dihydro-1,2,4- benzothiadiazine-1,1-dioxide; M.P. 168.5-170°C.

• Therapeutic Function

  Diuretic, Antihypertensive

Althiazide Upstream-Materialien And Downstream Produkte

Altizid Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global(43)Suppliers

5588-16-9, Althiazide Verwandte Suche: