(7aR,cis)3,4,7a,10a-Tetrahydro-5-methoxy-1H,12H-furo(3',2':4,5)-furo(2,3-h)pyrano(3,4-c)(1)-chromen-1,12-dion

Bezeichnung:(7aR,cis)3,4,7a,10a-Tetrahydro-5-methoxy-1H,12H-furo(3',2':4,5)-furo(2,3-h)pyrano(3,4-c)(1)-chromen-1,12-dion

CAS-Nr1165-39-5

Englisch Name:AFLATOXIN G1

CBNumberCB4702106

SummenformelC17H12O7

Molgewicht328.27

MOL-Datei1165-39-5.mol

Synonyma

(7aR,cis)3,4,7a,10a-tetrahydro-5-methoxy-1H,12H-furo[3',2':4,5]furo[2,3-h]pyrano[3,4-c]chromen-1,12-dion

(7aR,cis)3,4,7a,10a-Tetrahydro-5-methoxy-1H,12H-furo(3',2':4,5)-furo(2,3-h)pyrano(3,4-c)(1)-chromen-1,12-dion

(7aR,cis)3,4,7a,10a-Tetrahydro-5-methoxy-1H,12H-furo(3',2':4,5)-furo(2,3-h)pyrano(3,4-c)(1)-chromen-1,12-dion physikalisch-chemischer Eigenschaften

Schmelzpunkt	244-246 °C
alpha	D -556° (chloroform)
Siedepunkt	386.03°C (rough estimate)
Dichte	1.3358 (rough estimate)
Brechungsindex	1.4790 (estimate)
Flammpunkt	-11 °C
storage temp.	2-8°C
Löslichkeit	DMF: Soluble; DMSO: Soluble; Ethanol: Soluble; Methanol: Soluble
Aggregatzustand	Solid
Farbe	White to off-white
Wasserlöslichkeit	15mg/L(temperature not stated)
BRN	1299768
LogP	0.679 (est)
EPA chemische Informationen	Aflatoxin G1 (1165-39-5)

Sicherheit

Kennzeichnung gefährlicher	T+,T,F,Xn
R-Sätze:	45-26/27/28-65-48/23/24/25-36/38-11-46-39/23/24/25-23/24/25-36-20/21/22
S-Sätze:	53-28-36/37-45-62-26-16-7-36
RIDADR	UN 3462 6.1/PG 1
WGK Germany	3
RTECS-Nr.	LV1720000
F	10
HazardClass	6.1(a)
PackingGroup	I
HS Code	29322090
Giftige Stoffe Daten	1165-39-5(Hazardous Substances Data)
Toxizität	LD50 orally in day old duckling: 39.2 mg/50 gm body wt (Carnaghan)

Gefahreninformationscode (GHS)

AFLATOXIN G1 Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R45:Kann Krebs erzeugen.
R26/27/28:Sehr giftig beim Einatmen, Verschlucken und Berührung mit der Haut.
R65:Gesundheitsschädlich: kann beim Verschlucken Lungenschäden verursachen.
R48/23/24/25:Giftig: Gefahr ernster Gesundheitsschäden bei längerer Exposition durch Einatmen, Berührung mit der Haut und durch Verschlucken.
R36/38:Reizt die Augen und die Haut.
R11:Leichtentzündlich.
R46:Kann vererbbare Schäden verursachen.
R39/23/24/25:Giftig: ernste Gefahr irreversiblen Schadens durch Einatmen, Berührung mit der Haut und durch Verschlucken.
R23/24/25:Giftig beim Einatmen, Verschlucken und Berührung mit der Haut.
R36:Reizt die Augen.
R20/21/22:Gesundheitsschädlich beim Einatmen,Verschlucken und Berührung mit der Haut.
S-Sätze Betriebsanweisung:
S53:Exposition vermeiden - vor Gebrauch besondere Anweisungen einholen.
S28:Bei Berührung mit der Haut sofort abwaschen mit viel . . . (vom Hersteller anzugeben).
S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen).
S62:Bei Verschlucken kein Erbrechen herbeiführen. Sofort ärztlichen Rat einholen und Verpackung oder dieses Etikett vorzeigen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S16:Von Zündquellen fernhalten - Nicht rauchen.
S7:Behälter dicht geschlossen halten.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Chemische Eigenschaften
The aflatoxins are a group of molds produced by the fungus Aspergillus flavus. They are natural contaminants of fruits, vegetables, and grains. They are also described as a series of condensed ring heterocyclic compounds. They form colorless to pale yellow crystals. Practically insoluble in water.
Chemische Eigenschaften
yellow powder
Verwenden
Aflatoxin G1 from Aspergillus flavus has been used as a standard for the determination of aflatoxin in various samples.
Verwenden
Aflatoxin G1 is the major analogue of the green fluorescent family of bisfuranocoumarin mycotoxins produced by Aspergillus flavus and related species. Alfatoxins are one of the most potent mycotoxins known but are in fact "pre-toxins", requiring metabolic activation to the toxic principle. Aflatoxins are found widely in nature in trace amounts, particularly in grains and nuts. The toxicity of these metabolites was first recognised in the 1950s and their structures elucidated in 1963. Aflatoxins have been extensively reviewed.
Verwenden
Aflatoxins B1, B2, G1, G2 as secondary metabolites of fungal species such as Aspergillus flavus or Aspergillus parasiticus growing on a variety of foods (peanuts, nuts, spices, cereals). Aflatoxins a re a group of very carcinogenic mycotoxins with hepatotoxic effects.
Definition
ChEBI: Aflatoxin G is a member of coumarins.
Allgemeine Beschreibung
Certan Vial
Biochem/physiol Actions
Hepatocarcinogen. Food contaminant produced by Aspergillus flavus, a common soil fungus.
Sicherheitsprofil
Confirmed human carcinogen with experimental carcinogenic and neoplastigenic data. Poison by ingestion and intraperitoneal routes. Mutation data reported. When heated to decomposition it emits acrid smoke and irritating fumes. See also various aflatoxins
mögliche Exposition
Aflatoxins are a group of toxic metabolites produced by certain types of fungi. Aflatoxins are not commercially manufactured; they are naturally occurring contaminants that are formed by fungi on food during conditions of high temperatures and high humidity. Most human exposure to aflatoxins occurs through ingestion of contaminated food. The estimated amount of aflatoxins that Americans consume daily is estimated to be 0.15 0.50 μg. Grains, peanuts, tree nuts, and cottonseed meal are among the more common foods on which these fungi grow. Meat, eggs, milk, and other edible products from animals that consume aflatoxincontaminated feed may also contain aflatoxins. Aflatoxins can also be breathed in
Versand/Shipping
UN3172 Toxins, extracted from living sources, solid or liquid, Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required. UN2811 Toxic solids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required.
Inkompatibilitäten
Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides.
Waste disposal
Consult with environmental regulatory agencies for guidance on acceptable disposal practices. Generators of waste containing this contaminant (≥100 kg/mo) must conform with EPA regulations governing storage, transportation, treatment, and waste disposal. Use of oxidizing agents, such as hydrogen peroxide or 5% sodium hypochlorite bleach. Acids and bases may also be used.

(7aR,cis)3,4,7a,10a-Tetrahydro-5-methoxy-1H,12H-furo(3',2':4,5)-furo(2,3-h)pyrano(3,4-c)(1)-chromen-1,12-dion Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

1165-39-5, AFLATOXIN G1 Verwandte Suche:

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