MITRAGYNINE PICRATE

Bezeichnung:MITRAGYNINE PICRATE

CAS-Nr4098-40-2

Englisch Name:MITRAGYNINE PICRATE

CBNumberCB4682994

SummenformelC23H30N2O4

Molgewicht398.5

MOL-Datei4098-40-2.mol

MITRAGYNINE PICRATE physikalisch-chemischer Eigenschaften

Schmelzpunkt	92-95°C
alpha	D +39° (chloroform)
Siedepunkt	bp5 230-240°
Dichte	1.22±0.1 g/cm3 (20 ºC 760 Torr)
Flammpunkt	9℃
storage temp.	-20°C Freezer
Löslichkeit	Chloroform (Slightly), Methanol (Slightly)
pka	18.35±0.60(Predicted)
Aggregatzustand	Solid
Farbe	Light Orange to Dark Beige to Very Dark Yellow

Sicherheit

Kennzeichnung gefährlicher	F,T
R-Sätze:	11-23/24/25-39/23/24/25-36/37/38-22
S-Sätze:	7-16-36/37-45-26
RIDADR	UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany	1
HS Code	29339900
Giftige Stoffe Daten	4098-40-2(Hazardous Substances Data)

Gefahreninformationscode (GHS)

MITRAGYNINE PICRATE Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung
This alkaloid has been isolated from Mitragyna speciosa Korth, and is amorphous although it yields a series of crystalline salts and derivatives. The hydrochloride crystallizes as colourless leaflets from EtOH-Et20 with m.p. 243°C; the picrate forms thin, orange-red needles, m.p. 223-4°C and the methiodide is a pale yellow powder which, although amorphous, has a sharp melting point of 21 1. 5°C. The alkaloid also forms compounds with acetic acid, m.p. 142°C, decomposing at 175-6°, and with trichloroacetic acid, m.p. 157°C.
Mitragynine exerts a general depressant effect on plain muscle and facilitates the passage of autonomic impulses. It is, however, ineffective against pathogenic organisms.
Chemische Eigenschaften
White to Off-White Solid
Verwenden
Mitragynine is a neurochemical, having both stimulant and opiate-like effects depending on the dosage. Currently, Mitragynine is being investigated for its ability to treat hard drug addiction.
Verwenden
A neurochemical, having both stimulant and opiate-like effects depending on the dosage. Currently, Mitragynin is being investigated for its ability to treat hard drug addiction.
Definition
ChEBI: Mitragynine is a monoterpenoid indole alkaloid.
Einzelnachweise
Field., J. Chern. Soc., 119,887 (1921)
Raymond-Hamet, Millat., Bull. sci. pharrnacol., 40, 593 (1933)
lng, Raison., J. Chern. Soc., 986 (1939)
Loudon., Chern. Soc. Spec. Publ., 3, 12 (1955)
Hendrickson., Chern. & Ind., 713 (1961)
Joshi, Raymond-Hamet, Taylor., ibid, 573 (1963)
Pharmacology: Grewal., J. Pharrn. expo Ther., 46,251 (1932)

MITRAGYNINE PICRATE Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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