ELEUTHEROSIDE B1(RG)

ELEUTHEROSIDE B1(RG) Chemische Eigenschaften,Einsatz,Produktion Methoden

• Chemische Eigenschaften

  White crystalline powder, soluble in chloroform, derived from the dried rhizome of Acanthopanax senticosus.

• Biologische Aktivität

  Eleutheroside B1, a coumarin compound, has broad-spectrum anti-human influenza virus (influenza virus) activity with IC50 values of 64-125μg/ml. It mediates its anti-influenza activity through POLR2A and N-glycosylation. Eleutheroside B1 inhibits mRNA expression of multiple chemokine genes and influenza virus nucleoprotein (NP) gene with low cytotoxicity. Has antiviral and anti-inflammatory activity.

• in vitro

  Eeutheroside B1 (100 μg/ml; 24 hours) influences mRNA expression of host genes and virus genes in A549 cells.

  RT-PCR

  Cell Line:	Virus-infected A549 cells
  Concentration:	100 μg/ml
  Incubation Time:	24 hours
  Result:	The expression of host genes (MAN2A2, POLR2A) and virus genes (PA, PB1, PB2, HA) were decreased.

ELEUTHEROSIDE B1(RG) Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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