AROTINOLOL

Gefahreninformationscode (GHS)

• Bildanzeige (GHS)

  

• Alarmwort

  Warnung

• Gefahrenhinweise

  H302：Gesundheitsschädlich bei Verschlucken.

  H315：Verursacht Hautreizungen.

  H319：Verursacht schwere Augenreizung.

  H335：Kann die Atemwege reizen.

• Sicherheit

  P261：Einatmen von Staub vermeiden.

  P305+P351+P338：BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen.

AROTINOLOL Chemische Eigenschaften,Einsatz,Produktion Methoden

• Originator

  Arotinolol,ZYF Pharm

• Verwenden

  Arotinolol is both and alpha- and beta-adrenoceptor antagonist and is used to treat essential tremors and hypertension.

• Definition

  ChEBI: Arotinolol is a member of thiophenes and an aromatic amide.

• Manufacturing Process

  To a solution of 2-mercapto-4-(5'-carbamoyl-2'-thiophenyl)thiazole, 3.2 g in 20 ml of 0.3 % aqueous sodium hydroxide solution, 1-chloro-3-tbutylaminopropanol, 12.64 g in 20 ml of methanol was added, while the temperature was maintained at 20°C.
  The reaction solution was stirred at room temperature for 4 h, and then condensed to a half volume in vacuo. The residual solution, added with 100 ml of water, was extracted with chloroform. The chloroform extract was washed with water, dried over anhydrous magnesium sulfate and evaporated in vacuo to give 4.8 g of 2-(3'-t-butylamino-2'-hydroxypropylthio)-4-(5'-carbamoyl-2'- thiophenyl)thiazole, as crystals, melting point 234°-235.5°C (dec., recrystallized from methanol/water).
  In practice it is usually used as hydrochloride.

• Therapeutic Function

  Beta-adrenergic blocker

AROTINOLOL Upstream-Materialien And Downstream Produkte

AROTINOLOL Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global(85)Suppliers

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