aprinocarsen

aprinocarsen Chemische Eigenschaften,Einsatz,Produktion Methoden

• Verwenden

  Treatment of non-small cell lung cancer (antisense oligonucleotide; protein kinase C-alpha inhibitor).

• Trademarks

  Affinitak (Isis).

• Clinical Use

  Aprinocarsen is a phosphorothioate antisense agent targeted against protein kinase Cα, a protein that is implicated in malignant transformation and proliferation. It showed activity in Phase I and Phase II clinical trials against nonsmall-cell lung cancer when used in combination with cisplatin or the combination of cisplatin and gemcitabine.

151879-73-1, aprinocarsen Verwandte Suche: