Sulforidazin

sulforidazine Chemische Eigenschaften,Einsatz,Produktion Methoden

• Chemische Eigenschaften

  Thick Yellow Oil

• Originator

  Sulforidazine,ZYF Pharm Chemical

• Verwenden

  Thioridazine 2-Sulfone (Thioridazine EP Impurity E) is a major metabolite of Thioridazine (THD 2-SO2).

• Definition

  ChEBI: Sulforidazine is a member of phenothiazines.

• Manufacturing Process

  A mixture of 96.5 g 2-methylsulfonylphenothiazine, 50 g 2-(2-chloroethyl)-1- methylpiperidine, 62 g diethyl carbonate and 2 g sodium methylate was heated at 135°C for 1 hour and then at 180-190°C for 2.5 hours. The product was dissolved in benzene (500 ml) and the solution was extracted with 700 ml of 15% aqueous solution tartaric acid. The extract was washed with benzene. After addition of sodium carbonate solution to the extract was obtained a precipitate which was dissolved in benzene. This solution was washed with water and concentrated. 2-Methylsulfonyl-10-(2-(1-methyl-2- piperidyl)ethyl)phenothiazin was recrystallized from acetone, melting point 121-123°C.

• Therapeutic Function

  Neuroleptic

sulforidazine Upstream-Materialien And Downstream Produkte

Sulforidazin Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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