5H-Dibenzo[a,d]cyclohepten-5-on-O-[2-(methylamino)ethyl]oximmonohydrochlorid

5H-dibenzo[a,d]cyclohepten-5-one O-[2-(methylamino)ethyl]oxime monohydrochloride Chemische Eigenschaften,Einsatz,Produktion Methoden

• Originator

  Deparon,Aron,France,1981

• Verwenden

  Demexiptiline Hydrochloride is a tricyclic antidepressant that can also serve as a new potential antibacterial agent.

• Manufacturing Process

  1.15 g of Na are dissolved in 100 ml of absolute ethanol; 10 g of 5-oximino5H-dibenzo[a,d]cycloheptene are introduced, followed by boiling under reflux for 1 hour and evaporation to dryness. The residue is dissolved in dimethylformamide and part of the solvent is distilled off. The solution is now cooled to about 20°C and there are added 5.3 g of methylaminoethyl chloride which is prepared below 10°C from the corresponding hydrochloride by supersaturation with potassium carbonate. The mixture is then heated to 100°C for 1? hours. Finally, the mixture is evaporated to dryness, the residue dissolved in ether/water and the ethereal phase washed with water. After drying of the ethereal phase with potassium carbonate, 8.5 g of the hydrochloride of 5-β-methylaminoethoxyimino-5H-dibenzo[a,d]cycloheptene (melting point 232°C to 233°C) are obtained.

• Therapeutic Function

  Antidepressant

5H-dibenzo[a,d]cyclohepten-5-one O-[2-(methylamino)ethyl]oxime monohydrochloride Upstream-Materialien And Downstream Produkte

5H-Dibenzo[a,d]cyclohepten-5-on-O-[2-(methylamino)ethyl]oximmonohydrochlorid Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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