Isoaminil

isoaminile Chemische Eigenschaften,Einsatz,Produktion Methoden

• Originator

  Peracon,Toyo Jozo,Japan,1969

• Verwenden

  Treatment of rheumatoid arthritis.

• Definition

  ChEBI: Isoaminile is an alkylbenzene.

• Manufacturing Process

  140 cc of benzene and 24 g of α-isopropyl phenyl acetonitrile are added to 7.5 g of sodium amide. The mixture is stirred and refluxed for one hour. After cooling, 25 g of 2-dimethylamino-1-chloropropane, dissolved in 20 cc of benzene, are added and stirring and refluxing of the mixture is continued for 4 hours. After the reaction is completed, water is added to the reaction mixture. The benzene layer is separated from the aqueous layer and is extracted by means of 4N hydrochloric acid. The acid solution is rendered alkaline.
  The separated oil is taken up in ether. After drying the ethereal solution over sodium sulfate and distilling off the ether, the resulting crude α-isopropyl-α- (β'-dimethylamino propyl) phenyl acetonitrile is purified by distillation in a vacuum. The compound boils at 138° to 146°C/3 mm, according to US Patent 2,934,557.

• Therapeutic Function

  Antitussive

isoaminile Upstream-Materialien And Downstream Produkte

Isoaminil Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global(13)Suppliers

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