1,2-DI[(CIS)-9-OCTADECENOYL]-SN-GLYCEROL-3-PHOSPHO-[1-RAC-GLYCEROL] SODIUM SALT Struktur

1,2-DI[(CIS)-9-OCTADECENOYL]-SN-GLYCEROL-3-PHOSPHO-[1-RAC-GLYCEROL] SODIUM SALT

Bezeichnung:1,2-DI[(CIS)-9-OCTADECENOYL]-SN-GLYCEROL-3-PHOSPHO-[1-RAC-GLYCEROL] SODIUM SALT

CAS-Nr67254-28-8

Englisch Name:1,2-DI[(CIS)-9-OCTADECENOYL]-SN-GLYCEROL-3-PHOSPHO-[1-RAC-GLYCEROL] SODIUM SALT

CBNumberCB3774290

SummenformelC42H80NaO10P

Molgewicht799.06

MOL-Datei67254-28-8.mol

1,2-DI[(CIS)-9-OCTADECENOYL]-SN-GLYCEROL-3-PHOSPHO-[1-RAC-GLYCEROL] SODIUM SALT physikalisch-chemischer Eigenschaften

Flammpunkt	>200℃
storage temp.	-20°C
Löslichkeit	Chloroform: 2 mg/ml
Aggregatzustand	solution
Farbe	White to Almost white
InChIKey	IUVFCFQZFCOKRC-PDSLQGCUSA-M

Sicherheit

Kennzeichnung gefährlicher	Xn
R-Sätze:	22-38-40-48/20/22-67-36/38-20-63
S-Sätze:	36/37-26
RIDADR	UN 1888 6.1/PG 3
WGK Germany	3
HS Code	2919.90.5050

Gefahreninformationscode (GHS)

1,2-DI[(CIS)-9-OCTADECENOYL]-SN-GLYCEROL-3-PHOSPHO-[1-RAC-GLYCEROL] SODIUM SALT Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R22:Gesundheitsschädlich beim Verschlucken.
R38:Reizt die Haut.
R40:Verdacht auf krebserzeugende Wirkung.
R48/20/22:Gesundheitsschädlich: Gefahr ernster Gesundheitsschäden bei längerer Exposition durch Einatmen und durch Verschlucken.
S-Sätze Betriebsanweisung:
S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.
Beschreibung
1,2-Dioleoyl-sn-glycero-3-PG (DOPG) is a phospholipid containing the long-chain (18:1) fatty acid oleic acid inserted at the sn-1 and sn-2 positions. It can be used in the generation of micelles, liposomes, and other artificial membranes.
Verwenden
1,2-Dioleoyl-sn-glycero-3-phospho-rac-(1-glycerol) is an analog of 1,2-Dipalmitoyl-sn-glycero-3-phospho-rac-(1-glycerol) (D525495) which forms lipid bilayers. In the high temperature phase, the conformation of the chains is liquid-like. In the low temperature phases, the chains are stiff and parallel and they interdigitate.
Verwenden
18:1 (Δ9-Cis) PG has been used:
- in the preparation of giant unilamellar vesicle (GUV)
- in the preparation 200 nm large unilamellar vesicles (LUV)
- as a supplement in native macrophage membranes to generate membrane liposomes with an artificially modified electrical charge
Allgemeine Beschreibung
Phosphoglyceride (PG) are also referred as glycerophospholipid. It is an important component of membrane?bilayers. It has three-carbon backbone of glycerol, two long-chain?fatty acids,?esterified to?hydroxyl groups on carbons 1 and 2 of the glycerol and?phosphoric acid?esterified to the C3?hydroxyl group of glycerol. It is found at high levels in the membranes of all cells and at low levels in fat stores. 1,2-dioleoyl-sn-glycero-3-phospho-(1′-rac-glycerol) (DOPG)/18:1 (Δ9-Cis) PG?has two hydroxyl groups in its head group. It is an anionic lipid.
Biochem/physiol Actions
Remodeling of diacylphosphatidylglycerols by transesterification was studied in a phosphatidylglycerol-deficient microbe grown with exogenous DOPG.

1,2-DI[(CIS)-9-OCTADECENOYL]-SN-GLYCEROL-3-PHOSPHO-[1-RAC-GLYCEROL] SODIUM SALT Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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