Levomenol

Bezeichnung:Levomenol

CAS-Nr23089-26-1

Englisch Name:(-)-alpha-bisabolol

CBNumberCB3727948

SummenformelC15H26O

Molgewicht222.37

MOL-Datei23089-26-1.mol

Synonyma

Levomenol

Levomenol physikalisch-chemischer Eigenschaften

alpha	D -55.7°; D20 -51.02° (Günther)
Siedepunkt	bp12 153°
Dichte	d20 0.9211
Dampfdruck	0.015Pa at 20℃
FEMA	4666 \| ALPHA-BISABOLOL
Brechungsindex	n20/D 1.496
Flammpunkt	135 °C
storage temp.	-20°C
Löslichkeit	DMSO:100.0(Max Conc. mg/mL);449.7(Max Conc. mM)
pka	15.04±0.29(Predicted)
Aggregatzustand	Liquid
Farbe	Colorless to light yellow
Geruch (Odor)	at 100.00 %. fruity nutty coconut
Geruchsart	floral
Optische Aktivität	[α]/D -60±2°, neat
Wasserlöslichkeit	22mg/L at 20℃
JECFA Number	2031
LogP	5.5 at 25℃
CAS Datenbank	23089-26-1(CAS DataBase Reference)
EPA chemische Informationen	Levomenol (23089-26-1)

Sicherheit

RIDADR	UN 3082 9 / PGIII
WGK Germany	3
RTECS-Nr.	MJ9685000
HS Code	2906195000
Toxizität	LD50 in male, female mice, rats (ml/kg): 15.2, 15.0, 14.9, 15.6 orally (Habersang)

Gefahreninformationscode (GHS)

(-)-alpha-bisabolol Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung
Bisabolol, or more formally (-)-alpha-bisabolol, also known as levomenol, is a natural monocyclic sesquiterpene alcohol. Alpha-bisabolol, an unsaturated monocyclic sesquiterpene alcohol, is known as one of the “most-used herbal constituents” worldwide. Various therapeutic and biological properties of α-bisabolol in preventing oxidative stress, inflammatory disorders, infections, neurodegenerative diseases, cancers, and metabolic disorders have been reported. It is a common additive in many PCPs, including dental care products, skin moisturisers, sunscreens, and make-up products, due to its multiple biological activities.
Verwenden
Reference Standard in the analysis of herbal medicinal products
Verwenden
(-)-α-Bisabolol was used to investigate the leishmanicidal and cytotoxic activity of essential oil of Vanillosmopsis arborea.
Definition
ChEBI: (-)-alpha-Bisabolol is a sesquiterpenoid.
benefits
The benefits of Bisabolol (or α-bisabolol) on the skin include soothing, anti-aging, maintaining skin firmness, improving skin pigmentation and moisturising the skin to reduce the appearance of fine lines.
Allgemeine Beschreibung
(-)-α-Bisabolol is the major constituent of essential oil from leaves of Hymenocrater yazdianus.
Flammability and Explosibility
Not classified
Biochem/physiol Actions
α-Bisabolol is active against primary acute leukemia cells, including BCR-ABL(+) acute lymphoblastic leukemias. It is the inhibitor of voltage-dependent Ca(2+) channels in tracheal smooth muscle preparations of rat. It also inhibits human and rat glioma cell growth and survival. It is a potential new therapeutic agent against leishmaniasis.

Levomenol Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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