p-[[4-(Dimethylamino)phenyl]azo]benzolsulfonylchlorid

Bezeichnung:p-[[4-(Dimethylamino)phenyl]azo]benzolsulfonylchlorid

CAS-Nr56512-49-3

Englisch Name:DABSYL CHLORIDE

CBNumberCB3699737

SummenformelC14H14ClN3O2S

Molgewicht323.8

MOL-Datei56512-49-3.mol

Synonyma

p-[[4-(Dimethylamino)phenyl]azo]benzolsulfonylchlorid

p-[[4-(Dimethylamino)phenyl]azo]benzolsulfonylchlorid physikalisch-chemischer Eigenschaften

Schmelzpunkt	185 °C (dec.) (lit.)
Siedepunkt	483.6±30.0 °C(Predicted)
Dichte	1.29±0.1 g/cm3(Predicted)
storage temp.	room temp
Löslichkeit	DMF: soluble
Aggregatzustand	powder to crystaline
pka	3.27±0.10(Predicted)
Farbe	Orange to Brown to Dark red
Sensitive	Moisture Sensitive
BRN	3064095
CAS Datenbank	56512-49-3(CAS DataBase Reference)

Sicherheit

Kennzeichnung gefährlicher	C
R-Sätze:	34
S-Sätze:	26-36/37/39-45-27
RIDADR	UN 3261 8/PG 2
WGK Germany	3
RTECS-Nr.	DB8927800
F	10-21
HazardClass	8
PackingGroup	II
HS Code	29270000

Gefahreninformationscode (GHS)

DABSYL CHLORIDE Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R34:Verursacht Verätzungen.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen).
S27:Beschmutzte, getränkte Kleidung sofort ausziehen.
Chemische Eigenschaften
Dark red crystalline
Verwenden
For the qualitative and quantitative identification of amino acids and for the determination of N-terminal amino acids. Used in the determination of primary and secondary amines by HPLC.
Allgemeine Beschreibung
Amino groups are common to many biological compounds and many amines used in pharmaceuticals. Most of these compounds show weak absorption in direct HPLC analysis with UV-VIS detection. However, strongly absorbing derivatives of amines can be easily detected by HPLC with high sensitivity even when present at low concentrations. Primary and secondary amino groups are usually derivatized as aromatic derivatives by nucleophilic substitution reactions using reagents such as arylsulfonyl chlorides.
4-(Dimethylamino)azobenzene-4′-sulfonyl chloride, a well-known UV-labeling agent, is generally used for the derivatization of N-terminal amino acids, imidazole derivatives, polyamines, etc. prior to their chromatographic determination due to the former′s capacity to covalently bind to the substrates. Its derivatives typically absorb UV radiation between the range of 436-460 nm. This method of derivatization is regarded as superior compared to other methods owing to the simplicity of the procedure, high stability and reproducibility, best resolution of the analytes, etc.

p-[[4-(Dimethylamino)phenyl]azo]benzolsulfonylchlorid Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

56512-49-3, DABSYL CHLORIDE Verwandte Suche:

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