1,1-Dichlor-N-((dimethylamino)-sulfonyl)-1-fluor-N-(4-methyl-phenyl)methansulfenamid inatembarer Form)

Bezeichnung:1,1-Dichlor-N-((dimethylamino)-sulfonyl)-1-fluor-N-(4-methyl-phenyl)methansulfenamid inatembarer Form)

CAS-Nr731-27-1

Englisch Name:TOLYLFLUANID

CBNumberCB3438572

SummenformelC10H13Cl2FN2O2S2

Molgewicht347.26

MOL-Datei731-27-1.mol

Synonyma

Dichlor-N-[(dimethylamino)sulfonyl]fluor-N-(p-tolyl)methansulfenamid

1,1-Dichlor-N-((dimethylamino)-sulfonyl)-1-fluor-N-(4-methyl-phenyl)methansulfenamid inatembarer Form)

1,1-Dichlor-N-((dimethylamino)-sulfonyl)-1-fluor-N-(4-methyl-phenyl)methansulfenamid inatembarer Form) physikalisch-chemischer Eigenschaften

Schmelzpunkt	96°C
Siedepunkt	93℃
Dichte	1.5132 (rough estimate)
Dampfdruck	2 x 10^-5 Pa (20 °C)
Brechungsindex	1.6000 (estimate)
storage temp.	-20°C
Löslichkeit	soluble in DMSO, Methanol
Colour Index	45430
Wasserlöslichkeit	0.9 mg l^-1 (20 °C)
pka	-5.06±0.50(Predicted)
BRN	2949607
LogP	3.900
EPA chemische Informationen	Tolylfluanid (731-27-1)

Sicherheit

Kennzeichnung gefährlicher	T,N,T+
R-Sätze:	23-36/37/38-43-48/20-50/53-50-48/23-26
S-Sätze:	24-26-37-38-45-60-61-63-36/37/39-28
RIDADR	2588
WGK Germany	3
RTECS-Nr.	WO6560000
HazardClass	6.1(b)
PackingGroup	III
Giftige Stoffe Daten	731-27-1(Hazardous Substances Data)

Gefahreninformationscode (GHS)

TOLYLFLUANID Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R23:Giftig beim Einatmen.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
R43:Sensibilisierung durch Hautkontakt möglich.
R48/20:Gesundheitsschädlich: Gefahr ernster Gesundheitsschäden bei längerer Exposition durch Einatmen.
R50/53:Sehr giftig für Wasserorganismen, kann in Gewässern längerfristig schädliche Wirkungen haben.
S-Sätze Betriebsanweisung:
S24:Berührung mit der Haut vermeiden.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S37:Geeignete Schutzhandschuhe tragen.
S38:Bei unzureichender Belüftung Atemschutzgerät anlegen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen).
S60:Dieses Produkt und sein Behälter sind als gefährlicher Abfall zu entsorgen.
S61:Freisetzung in die Umwelt vermeiden. Besondere Anweisungen einholen/Sicherheitsdatenblatt zu Rate ziehen.
Verwenden
Tolylfluanid is used to control a wide range of fungal diseases on apples, grapes, strawberries and other fruit and storage diseases on many crops.
Verwenden
Tolylfluanid may be used as a reference standard for the determination of the analyte in nutraceutical formulations using dispersive liquid-liquid microextraction(DLLME) coupled with gas chromatography-mass spectrometry method.
Definition
ChEBI: A member of the class of sulfamides that is dichlofluanid in which the hydrogen at the para position of the phenyl group is replaced by a methyl group. A fungicide first marketed in 1971 and used in the cultivation of fruit and vegetables, as ell as in wood preservatives, it is no longer approved for use in the European Union.
Stoffwechselwegen
Tolylfluanid contains an unstable dichlorofluoromethylthio (sulfenyl) moiety that has been shown to undergo rapid hydrolytic and metabolic degradation to dimethylaminosulfotoluidide (2). By analogy with captan, presumably the dichlorofluoromethylthio moiety can be transferred to the sulfur atoms of cellular thiols such as cysteine and glutathione. Thus, in the presence of thiols tolylfluanid is probably cleaved at the N-S bond to form thiophosgene or its monofluoro analogue (3) and other gaseous products such as hydrogen sulfide, hydrogen chloride and carbonyl sulfide. Thiophosgene or its monofluoro analogue is rapidly hydrolysed by water. The dichlorofluoromethylthio group and thiophosgene may be intermediates in the formation of addition products, for example addition to cysteine affords thiazolidine-2-thione-4-carboxylica cid (4). A thiazolidine derivative of glutathione may also be formed. The main metabolic reactions in all media were cleavage of the N-S bond to give dimethylaminosulfotoluidide (2) followed by hydroxylation of the phenyl ring and oxidation of the methyl substituent on the phenyl ring. Glucoside conjugates were detected in plants and the cysteine adduct, thiazolidine-2- thione-4-carboxylic acid (4), was formed in rats.
Degradation
Tolylfluanid is hydrolysed rapidly in alkaline conditions. The hydrolytic DT₅₀ is about 12 days, 29 hours and <10 minutes at pH 4,7 and 9, respectively, at 22 °C. In the environment, hydrolysis is faster than photolysis (PM; PSD, 1995). Tolylfluanid does not absorb light of wavelength >295 nm and so photodegradation is unlikely to occur in the absence of photosensitisers.

1,1-Dichlor-N-((dimethylamino)-sulfonyl)-1-fluor-N-(4-methyl-phenyl)methansulfenamid inatembarer Form) Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

731-27-1, TOLYLFLUANID Verwandte Suche:

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