L-Homoserin

Bezeichnung:L-Homoserin

CAS-Nr672-15-1

Englisch Name:L-Homoserine

CBNumberCB2854094

SummenformelC4H9NO3

Molgewicht119.12

MOL-Datei672-15-1.mol

Synonyma

L-Homoserin

L-Homoserin physikalisch-chemischer Eigenschaften

Schmelzpunkt	203 °C (dec.)(lit.)
Siedepunkt	222.38°C (rough estimate)
alpha	-8.5 º (c=2, H2O 22 ºC)
Dichte	1.3126 (rough estimate)
Brechungsindex	1.4183 (estimate)
storage temp.	Store below +30°C.
Löslichkeit	1100g/l
Aggregatzustand	Crystalline Powder
pka	2.71(at 25℃)
Farbe	White to light yellow
Optische Aktivität	-8.825 (H2O) +18.326 (2 mol dm-3 HCl)
Wasserlöslichkeit	1100 g/L (30 ºC)
Merck	14,4739
BRN	1721681
InChIKey	UKAUYVFTDYCKQA-VKHMYHEASA-N
LogP	-1.289 (est)
CAS Datenbank	672-15-1(CAS DataBase Reference)

Sicherheit

R-Sätze:	36/37/38
S-Sätze:	24/25-44-35-26-28-7-4-3/9
WGK Germany	3
F	10
HS Code	29225000

Gefahreninformationscode (GHS)

L-Homoserine Chemische Eigenschaften,Einsatz,Produktion Methoden

S-Sätze Betriebsanweisung:
S24/25:Berührung mit den Augen und der Haut vermeiden.
Chemische Eigenschaften
white to light yellow crystalline powder
Verwenden
L-Homoserine is used in the biosynthesis of methionine, threonine and isoleucine. It is also used as an internal standard for neurotransmitter analysis and amino acids quantification.
Definition
ChEBI: L-homoserine is the L-enantiomer of homoserine. It has a role as a human metabolite, an algal metabolite, a Saccharomyces cerevisiae metabolite and an Escherichia coli metabolite. It is an enantiomer of a D-homoserine. It is a tautomer of a L-homoserine zwitterion.
Synthesis Reference(s)
Journal of the American Chemical Society, 80, p. 3147, 1958 DOI: 10.1021/ja01545a057
The Journal of Organic Chemistry, 24, p. 1794, 1959 DOI: 10.1021/jo01093a610
Allgemeine Beschreibung
L-Homoserine is a variant of serine with an additional carbon on its side chain.
Biochem/physiol Actions
L-Homoserine is synthesized by deoxidation process, catalysed by homoserine dehydrogenase. This is one of the steps in the synthesis of L-threonine. The carbon flux in in bacteria such as E. coli is maintained by this reaction.
läuterung methode
Likely impurities are N-chloroacetyl-L-homoserine, N-chloroacetyl-D-homoserine, L-homoserine, homoserine lactone, homoserine anhydride (formed in strong solutions of homoserine if slightly acidic). It cyclises to the lactone in strongly acidic solution. It crystallises from water by adding 9 volumes of EtOH. [Greenstein & Winitz The Chemistry of the Amino Acids J. Wiley, Vol 3 pp 2612-2616 1961, Beilstein 4 IV 3187.]

L-Homoserine Upstream-Materialien And Downstream Produkte

L-Homoserin Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

672-15-1, L-Homoserine Verwandte Suche:

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