Ricinin

Bezeichnung:Ricinin

CAS-Nr524-40-3

Englisch Name:RICININE

CBNumberCB2202950

SummenformelC8H8N2O2

Molgewicht164.16

MOL-Datei524-40-3.mol

Synonyma

Ricinin

Ricinin physikalisch-chemischer Eigenschaften

Schmelzpunkt	201.5°
Siedepunkt	291.62°C (rough estimate)
Dichte	1.2739 (rough estimate)
Brechungsindex	1.6000 (estimate)
Flammpunkt	2℃
storage temp.	-20°C
Löslichkeit	DMSO: slightly soluble,Methanol: slightly soluble
Aggregatzustand	A solid
pka	-4.93±0.62(Predicted)
Wasserlöslichkeit	2.7g/L(10 ºC)
CAS Datenbank	524-40-3

Sicherheit

Kennzeichnung gefährlicher	T,Xn,F
R-Sätze:	25-36-20/21/22-11
S-Sätze:	45-36/37-16
RIDADR	UN 2811 6.1 / PGIII
WGK Germany	3
RTECS-Nr.	QT3100000

Gefahreninformationscode (GHS)

RICININE Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung
First isolated by Tuson from the seeds of Ricinus communis (castor-oil seed), the alkaloid was subsequently examined by Soave, Schultze and Evans. The base crystallizes from H20 in colourless prisms or leaflets and sublimes at 170-lS0°C/ 20 mm. It is soluble in hot H20 or CHCI3, only sparingly so in EtOH and insoluble in petroleum ether, is neutral in reaction, optically inactive and forms no normal salts although the mercurichloride, m.p. 204°C has been prepared. The alkaloid reduces KMn04 and may be hydrolyzed by alkalies to MeOH and ricininic acid which forms brilliant, slender needles, m.p. 296-8°C (dec.). The structure of ricinine has been confirmed by synthesis from 4-chloroquinoline. Other syntheses have also been achieved. The base is not particularly toxic and the poisonous character of castor-oil seeds has been shown to be due to a more complex substance, ricin, the toxicity of which may be destroyed by heating.
Chemische Eigenschaften
White Solid
Verwenden
Ricinine is an alkaloid extract from the seeds of the castor-oil plant (Ricinus communalis). Ricinine is a central nervous system stimulant that could potentially be a cognition-enhancing agent used for the treatment of human amnesias. Ricinine also has bactericidal effects on three pests and heptaprotective activity.
Verwenden
An alkaloid extract from the seeds of the castor-oil plant (Ricinus communalis). It is a central nervous system stimulant that could potentially be a cognition-enhancing agent used for the treatment of human amnesias. It also has bactericidal effects on t
Definition
ChEBI: Ricinine is a pyridine alkaloid, a pyridone and a nitrile.
Hazard
Toxic by ingestion.
Sicherheitsprofil
A poison by ingestion and subcutaneous route. When heated to decomposition it emits toxic vapors of NOx.
Einzelnachweise
Tuson.,J. Chern. Soc., 17,195 (1864)
Soave., Chern. Soc. Abstr., i, 386 (1896)
Schultze., ibid, i, 42 (1898)
Evans., J. Arner. Chern. Soc., 22, 39 (1900)
Maqueen, Philippe., Cornpt. rend., 138, 506 (1904)
Maqueen, Philippe., ibid, 139, 840 (1904)
Winterstein, Keller, Weinhagen., Arch. Pharrn., 255,513 (1917)
Bottcher., Ber., 51,673 (1918)
Spath, Tschelnitz., Monatsh., 42,251 (1921)
Spath, Koller., Ber., 56, 880, 2454 (1923)
Spath, Koller., ibid, 58,2124 (1925)
Schroeter et ai., ibid, 65, 432 (1932)
Reitmann., Chern. Abstr., 29,4359 (1935)

Ricinin Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

524-40-3, RICININE Verwandte Suche:

Send Inquriy