SODIUM PROPIONATE Struktur

SODIUM PROPIONATE

Bezeichnung:SODIUM PROPIONATE

CAS-Nr6700-17-0

Englisch Name:SODIUM PROPIONATE

CBNumberCB2157845

SummenformelC3H5NaO2

Molgewicht96.06

MOL-Datei6700-17-0.mol

SODIUM PROPIONATE physikalisch-chemischer Eigenschaften

Schmelzpunkt	285-286 °C(lit.)
Löslichkeit	H₂O: 0.1 g/mL, clear

Sicherheit

Kennzeichnung gefährlicher	Xn
R-Sätze:	21
S-Sätze:	36/37
WGK Germany	1
RTECS-Nr.	UF7525000
F	3

Gefahreninformationscode (GHS)

SODIUM PROPIONATE Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R21:Gesundheitsschädlich bei Berührung mit der Haut.
S-Sätze Betriebsanweisung:
S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.
Chemische Eigenschaften
Sodium propionate occurs as colorless transparent crystals or as a granular, free-flowing, crystalline powder. It is odorless, or with a slight characteristic odor, and is deliquescent in moist air. Sodium propionate has a characteristic, slightly cheeselike taste, although by itself it is unpalatable.
Verwenden
Pharmaceutic aid (preservative).
Verwenden
Sodium Propionate Hydrate is a food preservative used for its antifungal ability towards grain products.
Vorbereitung Methode
Sodium propionate is prepared by the reaction of propionic acid with sodium carbonate or sodium hydroxide.
Pharmazeutische Anwendungen
As an excipient, sodium propionate is used in oral pharmaceutical formulations as an antimicrobial preservative. Like propionic acid, sodium propionate and other propionic acid salts are fungistatic and bacteriostatic against a number of Gram-positive cocci. Propionates are more active against molds than is sodium benzoate, but have essentially no activity against yeasts.
Therapeutically, sodium propionate has been used topically in concentrations up to 10% w/w alone or in combination with other propionates, caprylates, or other antifungal agents, in the form of ointments or solutions for the treatment of dermatophyte infections. Eye drops containing 5% w/v sodium propionate have also been used.
In food processes, particularly baking, sodium propionate is used as an antifungal agent; it may also be used as a flavoring agent in food products. In veterinary medicine, sodium propionate is used therapeutically as a glucogenic substance in ruminants.
Sicherheit(Safety)
Sodium propionate and other propionates are used in oral pharmaceutical formulations, food products, and cosmetics. The free acid, propionic acid, occurs naturally at levels up to 1% w/w in certain cheeses.
Following oral consumption, propionate is metabolized in mammals in a manner similar to that of fatty acids. Toxicity studies in animals have shown sodium propionate and other propionates to be relatively nontoxic materials.(2,3) In veterinary medicine, sodium propionate is used as a therapeutic agent for cattle and sheep.
In humans, 6 g of sodium propionate has been administered daily without harm.(2) However, allergic reactions to propionates can occur.
LD50 (mouse, oral): 6.33 g/kg
LD50 (mouse, SC): 2.1 g/kg
LD50 (rabbit, skin): 1.64 g/kg
Lager
Sodium propionate is deliquescent and should therefore be stored in an airtight container in a cool, dry place.
Inkompatibilitäten
Incompatibilities for sodium propionate are similar to those of other weak organic acids.
Regulatory Status
GRAS listed. Accepted for use as a food additive in Europe. In cheese products, propionates are limited to 0.3% w/w concentration; a limit of 0.32% w/w is applied in flour and white bread rolls, while a limit of 0.38% w/w is applied in whole wheat products.
Included in the FDA Inactive Ingredients Database (oral capsules, powder, suspensions, and syrups). Included in nonparenteral medicines licensed in the UK. Included in the Canadian List of Acceptable Non-medicinal Ingredients.

SODIUM PROPIONATE Upstream-Materialien And Downstream Produkte

SODIUM PROPIONATE Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

6700-17-0, SODIUM PROPIONATE Verwandte Suche:

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