Etofyllinclofibrat

ETOFYLLINE CLOFIBRATE Chemische Eigenschaften,Einsatz,Produktion Methoden

• Originator

  Duolip,Merckle,W. Germany,1981

• Verwenden

  Duolip (L. Merckle, Germany).

• Definition

  ChEBI: Etofylline clofibrate is an oxopurine.

• Manufacturing Process

  107.3 g (0.5 mol) 2-(p-chlorophenoxy)isobutyric acid and 56.0 g (0.25 mol) 7-hydroxyethyltheophylline were suspended together in 250 ml xylene. They were heated together for 15 hours in a water separator following the addition of 1.5 g p-toluenesulfonic acid. The solution was next agitated with dilute sodium bicarbonate solution (0.5 mol NaHCO3), water washed and evaporated in a rotary evaporator.
  The residue was then crystallized from isopropanol, yielding 58.0 g (55% yield) of 1-(7-theophyllinyl)-2-ethyl[2-(p-chlorophenoxy)-isobutyrate] . The compound had a melting point of 131°C to 132°C.

• Therapeutic Function

  Antihyperlipidemic

ETOFYLLINE CLOFIBRATE Upstream-Materialien And Downstream Produkte

Etofyllinclofibrat Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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