Baicalin-7-diglucoside

Baicalin-7-diglucoside Chemische Eigenschaften,Einsatz,Produktion Methoden

• Chemische Eigenschaften

  Soluble in methanol, ethanol, water, etc., insoluble in petroleum ether and chloroform. Derived from Oroxylum indicum, Bignoniaceae

• Verwenden

  Oroxin B is a component of the seed of O. (oroxylum) indicum and is used in traditional Chinese medicine for antiinflammatory, analgesic and other functions. It also has been observed to selectively induce tumor-suppressive ER stress and inhibits tumor-adaptive ER stress in B-lymphoma cells attenuating tumor growth.

• in vivo

  Oroxin B (30 mg/kg, i.p., 28 days) induces malignant lymphoma cell ER stress, and inhibits tumor growth in human lymphoma cell (Raji cell) xenograft model^[2].
  Oroxin B (160 μM of 10 μL, injected into the knee joints of mice) protects articular cartilage in destabilized medial meniscus (DMM) induced mice OA^[3].
  Oroxin B (200 mg/kg/day, oral gavage) relieves hepatic inflammation and inhibits MAFLD progression in HFD-fed rats^[4].
  

  Animal Model:	Human lymphoma cell (Raji cell) xenograft model[2]
  Dosage:	30 mg/kg
  Administration:	i.p., 28 days
  Result:	Induced malignant lymphoma cell ER stress. Inhibited tumor growth. Prolonged overall survival of tumor-bearing mice.

  Animal Model:	HFD-fed rats[4]
  Dosage:	200 mg/kg/day
  Administration:	oral gavage
  Result:	Reduced the levels of plasma lipids, LPS, IL-6, and TNF-α. Inhibited liver fibrosis by reducing collagen deposition.

Baicalin-7-diglucoside Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global(204)Suppliers

114482-86-9, Baicalin-7-diglucoside Verwandte Suche: