Misoprostol Acid

Bezeichnung:Misoprostol Acid

CAS-Nr112137-89-0

Englisch Name:Misoprostol Acid

CBNumberCB0713294

SummenformelC21H36O5

Molgewicht368.51

MOL-Datei112137-89-0.mol

Misoprostol Acid physikalisch-chemischer Eigenschaften

Siedepunkt	538.3±50.0 °C(Predicted)
Dichte	1.118±0.06 g/cm3(Predicted)
storage temp.	-20°C
Löslichkeit	Chloroform
pka	4.77±0.10(Predicted)
Aggregatzustand	Yellow viscous oil.
Farbe	Pale Yellow
Stabilität	Temperature Sensitive

Sicherheit

Kennzeichnung gefährlicher	T
R-Sätze:	45-60-61-25-36/37/38
S-Sätze:	53-22-36/37/39-45-26
RIDADR	UN 2810 6.1/PG 3
WGK Germany	2
HazardClass	6.1

Gefahreninformationscode (GHS)

Misoprostol Acid Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R45:Kann Krebs erzeugen.
R60:Kann die Fortpflanzungsfähigkeit beeinträchtigen.
R61:Kann das Kind im Mutterleib schädigen.
R25:Giftig beim Verschlucken.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S53:Exposition vermeiden - vor Gebrauch besondere Anweisungen einholen.
S22:Staub nicht einatmen.
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen).
Beschreibung
Misoprostol is a prostaglandin E₁ analog with agonist activity mediated by EP₂, EP₃, and EP₄ receptors. It has been shown to inhibit the formation of gastric lesions in rats (ED₅₀ = 0.31 μg/kg), inhibit superoxide generation in human neutrophils (EC₅₀ = 0.35 μM), and relax fetal rabbit ductus arteriosus (EC₅₀ = 0.36 nM) in a concentration dependent manner. Misoprostol is commonly used in clinical medicine for the prevention of peptic ulcer disease. It has also been used in conjunction with mifepristone (RU-486; ) for the oral induction of first trimester abortion. Misoprostol contains a C-1 methyl ester and is readily absorbed and rapidly hydrolyzed in humans to the active free acid.
Chemische Eigenschaften
Pale Yellow Gel
Verwenden
Misoprostol Acid is a prostaglandin E1 analog with agonist activity mediated by EP2, EP3, and EP4 receptors. It has been shown to inhibit the formation of gastric lesions in rats (ED50 = 0.31 μg/kg), inhibit superoxide generation in human neutrophils (EC50 = 0.35 μM), and relax fetal rabbit ductus arteriosus (EC50 = 0.36 nM) in a concentration dependent manner. Misoprostol is commonly used in clinical medicine for the prevention of peptic ulcer disease. It has also been used in conjunction with mifepristone (RU-486; ) for the oral induction of first trimester abortion. Misoprostol contains a C-1 methyl ester and is readily absorbed and rapidly hydrolyzed in humans to the active free acid.
Verwenden
A cytoprotective prostaglandin PGE1 analogue.
Verwenden
A metabolite of Misoprostol. Cytoprotective PGE1 analog that prevents NSAID-induced gastric ulceration
Biochem/physiol Actions
Misoprostol is a synthetic prostaglandin E1 (PGE1) analogue use to prevent non steroidal anti inflammatory drug-induced (NSAID) gastric ulcers; as a labor inducing and postpartum hemorrhage treatment agent.

Misoprostol Acid Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

112137-89-0, Misoprostol Acid Verwandte Suche:

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