3,3'-Iminodipropiononitril
Bezeichnung:3,3'-Iminodipropiononitril
CAS-Nr111-94-4
Englisch Name:3,3'-IMINODIPROPIONITRILE
CBNumberCB0387000
SummenformelC6H9N3
Molgewicht123.16
MOL-Datei111-94-4.mol
Synonyma
3,3'-Iminodipropiononitril
3,3'-Iminodipropiononitril physikalisch-chemischer Eigenschaften
| Schmelzpunkt | -6 °C |
| Siedepunkt | 205 °C25 mm Hg(lit.) |
| Dichte | 1.02 g/mL at 25 °C(lit.) |
| Brechungsindex | n |
| Flammpunkt | >230 °F |
| storage temp. | 2-8°C |
| Aggregatzustand | clear liquid |
| pka | 6.13±0.19(Predicted) |
| Farbe | Colorless to Light yellow to Light orange |
| Wasserlöslichkeit | Soluble in water. |
| Stabilität | Stable, but moisture sensitive. Reaction with moisture may lead to a build up of pressure in sealed bottles. Combustible. Incompatible with strong oxidizing agents. |
| CAS Datenbank | 111-94-4(CAS DataBase Reference) |
| EPA chemische Informationen | 3,3'-Iminobispropanenitrile (111-94-4) |
| Kennzeichnung gefährlicher | Xi |
| R-Sätze: | 36/37/38 |
| S-Sätze: | 26 |
| RIDADR | UN 3334 |
| WGK Germany | 2 |
| RTECS-Nr. | UG2975000 |
| TSCA | Yes |
| HS Code | 29269095 |
| Giftige Stoffe Daten | 111-94-4(Hazardous Substances Data) |
| Toxizität | A neurotoxic synthetic nitrile that causes proximal axonopathies in the spinal cord and brain stem. The proximal axonal swellings are due to interruption of slow axonal transport, resulting in a large accumulation of neurofilaments. Secondary to these effects is a progressive atrophy of the distal axon, secondary demyelination, and gliosis. The slow axonal transport defect appears to be selective, as little evidence for perturbations in fast axonal transport have been reported. Behaviorally, IDPN induces hyperactivity, a “waltzing syndrome,” circling and head-rolling in mice and rats. IDPN intoxication has been advanced as a model for certain motor neuron degenerative diseases such as amyotropic lateral sclerosis (ALS) and hereditary canine spinal muscular atrophy (HCSMA). |
