Dichlorison-21-acetat

DICHLORISONE ACETATE Chemische Eigenschaften,Einsatz,Produktion Methoden

• Originator

  Diloderm ,Schering,US,1960

• Verwenden

  antipruretic

• Definition

  ChEBI: Dichlorisone is a corticosteroid hormone.

• Manufacturing Process

  A solution of 1.0 g of 1,4,9(11)-pregnatriene-17α,21-diol-3,20-dione-21- acetate and 5.0 g of lithium chloride in 40 ml of glacial acetic acid is treated
  with 0.410 g of N-chlorosuccinimide, followed by 0.104 g of anhydrous hydrogen chloride dissolved in 2.5 ml of tetrahydrofuran. The reaction mixture is stirred for 2 hours and poured into ice water. The crude product is filtered and washed with water to give 1.12 g of solid material, which is recrystallized from acetone-hexane to give substantially pure 9α,11β-dichloro-1,4- pregnadiene-17α,21-diol-3,20-dione-21-acetate; MP 246°C to 253°C (dec.).

• Trademarks

  Diloderm (Schering).

• Therapeutic Function

  Antipruritic, Antihistaminic, Appetite stimulant

DICHLORISONE ACETATE Upstream-Materialien And Downstream Produkte

Dichlorison-21-acetat Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global(38)Suppliers

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