Secoisolariciresinol diglucoside

Secoisolariciresinol diglucoside Chemische Eigenschaften,Einsatz,Produktion Methoden

• Biologische Aktivität

  Secoisolariciresinol diglucoside ((S,S)-SDG), the major lignan in whole wheat flaxseed, has anti-inflammatory, antioxidant, anti-mutagenic, antimicrobial, anti-obesity, hypolipidemic and neuroprotective effects.

• in vitro

  Secoisolariciresinol diglucoside (1-500 μM) possesses strong reducing power and high free radical scavenging activity for hydroxyl, peroxyl and DPPH free radicals.

• in vivo

  Secoisolariciresinol diglucoside (4 mg/mouse; a single po) diminishes leukocyte adhesion and migration across blood-brain barrier (BBB) in neuroinflammation.

  Animal Model: < /td>	Hand feeding mice (10 weeks old, male) are injected with TNFα
  Dosage:	4 mg/mouse
  Administration:	Po 2 h before ic administration of TNFα
  Result:	Attenuated adhesion of leukocytes to the endothelium by 50% and attenuated migration of leukocytes across the BBB by 64%.

Secoisolariciresinol diglucoside Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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