1-(2,4,5-Trimethoxyphenyl)ethan-1-on

Gefahreninformationscode (GHS)

• Bildanzeige (GHS)

  

• Alarmwort

  Warnung

• Gefahrenhinweise

  H319：Verursacht schwere Augenreizung.

• Sicherheit

  P305+P351+P338：BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen.

2',4',5'-TRIMETHOXYACETOPHENONE Chemische Eigenschaften,Einsatz,Produktion Methoden

• synthetische

  Preparation by reaction of acetyl chloride with hydroxyhydroquinone trimethyl ether in the presence of aluminium chloride.

• Synthesis Reference(s)

  Journal of Medicinal Chemistry, 33, p. 1155, 1990 DOI: 10.1021/jm00166a012

• Synthese

  2,4,5-Trimethoxy acetophenone is synthesised using 2-Hydroxy-4,5-dimethoxy acetophenone as raw material by chemical reaction. The specific synthesis steps are as follows:
  2-Hydroxy-4,5-dimethoxyacetophenone(5 g,0.0255 mole) in dry acetone (100 ml)is refluxed for 30 hr under anhydrous conditions with dimethyl sulphate (2.8 ml,3.78 g,0.03 mole)and ignited potassium carbonate (20 g).The mixture is filtered and the inorganic residue washed with hot acetone (2 x 20 ml).The combined acetone solution is distilled and the oily residue macerated with crushed ice.The solid product is filtered,washed with water and dried.It is crystallised from benzene as colourless needles.Yield 4.5g (84.1%).M.p.97(lit.m.p.102).
  

1-(2,4,5-Trimethoxyphenyl)ethan-1-on Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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