alpha-香附酮
- CAS号:473-08-5
- 英文名:alpha-Cyperone
- 中文名:alpha-香附酮
- CBNumber:CB9547438
- 分子式:C15H22O
- 分子量:218.33
- MOL File:473-08-5.mol
- 熔点 :232 °C
- 沸点 :177 °C(Press: 20 Torr)
- 密度 :0.9946 g/cm3(Temp: 25 °C)
- 储存条件 :Sealed in dry,Store in freezer, under -20°C
- 溶解度 :Chloroform (Slightly), Methanol (Slightly)
- 形态 :Oil
- 颜色 :Colourless to Pale Yellow
- LogP :4.220 (est)
- 安全说明 :24/25
- 海关编码 :29143990
alpha-香附酮性质、用途与生产工艺
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简介
alpha-香附酮为黄色液体,易溶于甲醇、水,来源于香附,益智仁,莎草科植物香附(莎草) Cyperus rotundus L. 的根茎。
- 生物活性 α-Cyperone (alpha-cyperone) 是香附子Cyperus rotundus的主要活性成分,表现出了如抗毒力、抗原毒性和抗菌活性等生物活性。α-Cyperone (alpha-cyperone) 与COX-2、IL-6、Nck-2、Cdc42 和 Rac1 的表达下调有关。
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靶点
Human Endogenous Metabolite
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体外研究
The anti-inflammatory activity of alpha-Cyperone (α-Cyperone) is associated with the down-regulation of COX-2 and IL-6 via the negative regulation of the NFκB pathway in LPS-stimulated RAW 264.7 cells.
alpha-Cyperone (α-Cyperone) binds and interacts with tubulin and is capable of distinctly destabilizing microtubule polymerization. The effect of this interaction could result in reduction of inflammation which would be highly beneficial for treatment of inflammatory diseases such as AD. One microliter of alpha-Cyperone was dissolved in DMSO (1:1 v/v) and it was further diluted in double distilled water (ddH2O) to a final volume of 20 microliter. - 化学性质 黄色液体,易溶于甲醇、水,来源于香附,益智仁,莎草科植物香附(莎草) Cyperus rotundus L. 的根茎。
- 用途 α-香附酮具有解热镇痛的作用。
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用途
用于含量测定/鉴定/药理实验等
药理药效:疏肝解郁,养血调经止痛
- 更新日期:2024/11/08
- 产品编号:HY-N0710
- 产品名称:alpha-香附酮 alpha-Cyperone
- CAS编号:473-08-5
- 包装:5mg
- 价格:550元
- 更新日期:2024/11/08
- 产品编号:HY-N0710
- 产品名称:alpha-香附酮 alpha-Cyperone
- CAS编号:473-08-5
- 包装:10mg
- 价格:853元
- 公司名称:Carbosynth
- 联系电话:--
- 电子邮件:sales@carbosynth.com
- 国家:英国
- 产品数:6005
- 优势度:58