ChemicalBook CAS数据库列表 SMER28
SMER28
- CAS号:307538-42-7
- 英文名:SMER 28
- 中文名:SMER28
- CBNumber:CB92561083
- 分子式:C11H10BrN3
- 分子量:264.12
- MOL File:307538-42-7.mol
SMER28化学性质
- 熔点 :171-173 °C
- 沸点 :391.6±32.0 °C(Predicted)
- 密度 :1.520±0.06 g/cm3(Predicted)
- 储存条件 :2-8°C
- 溶解度 :DMSO: >20mg/mL
- 形态 :solid
- 酸度系数(pKa) :6.12±0.50(Predicted)
- 颜色 :Beige
- 稳定性 :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
安全信息
SMER28性质、用途与生产工艺
- 生物活性 SMER28 是一个调节自噬的、独立于 mTOR 信号通路机制的小分子阳性调节剂，能够阻止β淀粉样蛋白肽的累积。
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体外研究
SMER28 (5-200 μM; 24 hours) shows a dose dependent decline of cell viability.
Cell Viability Assay
Cell Line: MMS1 cells Concentration: 5, 25, 50, 75, 100, 150, 200 μM Incubation Time: 24 hours Result: Showed a dose dependent decline of cell viability. -
体内研究
SMER28 (15-65 mg/kg; i.h.; daily, two days before irradiation and during the three days of irradiation) significantly protects against post-irradiation weight loss and enhances survival of mice at 65 mg/kg.
Animal Model: 14 to 16 weeks male mice (Balb/c) Dosage: 15, 65 mg/kg Administration: Subcutaneous injection; two days before irradiation and during the three days of irradiation (total 5 days) Result: Significantly protected against post-irradiation weight loss and enhanced survival of mice at 65 mg/kg.
SMER28上下游产品信息
上游原料
下游产品
SMER28 试剂级价格
- 更新日期：2024/08/19
- 产品编号：HY-100200
- 产品名称：SMER28
- CAS编号：
- 包装：1 mg
- 价格：250元
- 更新日期：2024/08/19
- 产品编号：HY-100200
- 产品名称：SMER28 SMER28
- CAS编号：307538-42-7
- 包装：5mg
- 价格：500元
SMER28生产厂家
- 公司名称：TORONTO
- 联系电话：--
- 电子邮件：info@trc-canada.com
- 国家：加拿大
- 产品数：6088
- 优势度：71
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