ChemicalBook CAS数据库列表 茚达酮
茚达酮
- CAS号:96478-43-2
- 英文名:Irindalone
- 中文名:茚达酮
- CBNumber:CB91117135
- 分子式:C24H29FN4O
- 分子量:408.518
- MOL File:96478-43-2.mol
茚达酮化学性质
- 储存条件 :Store at -20°C
- 溶解度 :Soluble in DMSO
茚达酮性质、用途与生产工艺
- 生物活性 Irindalone 是一种 5-羟色胺 (5-HT2) 拮抗剂。
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靶点
5-HT 2 Receptor
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体外研究
Irindalone causes a concentration-related inhibition of serotonin-induced contractions and shifts the serotonin curve to the right. Irindalone is more potent in inhibiting the serotonin-induced contractions. Irindalone has a similar profile in vitro, with a high affinity for serotonin 5-HT 2 receptors and about a 10 times lower affinity for α 1 -adrenoceptors.
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体内研究
Irindalone dose dependently lowers the blood pressure in spontaneously hypertensive rats (SHR) and renal hypertensive dogs.
茚达酮上下游产品信息
上游原料
下游产品
茚达酮生产厂家
- 公司名称：Leancare Ltd.
- 联系电话：--
- 电子邮件：enquiry@leancare.co.uk
- 国家：英国
- 产品数：6460
- 优势度：42
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