茚达酮
中文名称:茚达酮
英文名称:Irindalone
CAS号:96478-43-2
分子式:C24H29FN4O
分子量:408.51
EINECS号:
Mol文件:96478-43-2.mol
茚达酮 性质
| 熔点 | 88-90 °C |
|---|---|
| 沸点 | 605.690±55.00 °C(Press: 760.00 Torr)(predicted) |
| 密度 | 1.219±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) |
| 储存条件 | Store at -20°C |
| 溶解度 | 溶于二甲基亚砜 |
| 酸度系数(pKa) | 14.519±0.20(predicted) |
茚达酮 用途与合成方法
Irindalone 是一种 5-羟色胺 (5-HT2) 拮抗剂。
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5-HT 2 Receptor
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Irindalone causes a concentration-related inhibition of serotonin-induced contractions and shifts the serotonin curve to the right. Irindalone is more potent in inhibiting the serotonin-induced contractions. Irindalone has a similar profile in vitro, with a high affinity for serotonin 5-HT 2 receptors and about a 10 times lower affinity for α 1 -adrenoceptors.
Irindalone dose dependently lowers the blood pressure in spontaneously hypertensive rats (SHR) and renal hypertensive dogs.
茚达酮供应商 更多
TargetMol中国（陶术生物）
联系电话：4008200310 15002144251
产品介绍：
中文名称：化合物 Irindalone
英文名称：Irindalone
CAS：96478-43-2
包装信息：50mg/RMB 13800;100mg/RMB 17500;25mg/RMB 10600
