ChemicalBook CAS数据库列表 DIPHTHERIA TOXIN
DIPHTHERIA TOXIN
- CAS号:92092-36-9
- 英文名:DIPHTHERIA TOXIN
- 中文名:DIPHTHERIA TOXIN
- CBNumber:CB7710959
- 分子式:
- 分子量:0
- MOL File:Mol file
DIPHTHERIA TOXIN化学性质
- 储存条件 :2-8°C
- 形态 :lyophilized powder
安全信息
- 危险品标志 :T+
- 危险类别码 :28
- 安全说明 :22-24/25-45-36/37-28
- 危险品运输编号 :3172
- WGK Germany :3
- RTECS号 :XW5807200
- 危险等级 :6.1(a)
- 包装类别 :I
DIPHTHERIA TOXIN性质、用途与生产工艺
- 生物活性 Diphtheria toxin CRM197 是白喉毒素的一个无毒变种，具有一个单一的突变 (52 位的甘氨酸到谷氨酸的替代)，可以消除其毒性。CRM197 作为载体蛋白广泛应用于疫苗中。
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体外研究
Diphtheria toxin CRM197 is an enzymatically inactive and nontoxic form of diphtheria toxin that contains a single amino acid substitution (G52E). Being naturally nontoxic, CRM197 is an ideal carrier protein for conjugate vaccines against encapsulated bacteria and is currently used to vaccinate children globally against Haemophilus influenzae, pneumococcus, and meningococcus.
Diphtheria toxin, a single polypeptide secreted by lysogenic strains of Corynebacterium diphtheria , causes the disease diphtheria in humans by gaining entry into the cytoplasm of cells and inhibiting protein synthesis.
DIPHTHERIA TOXIN上下游产品信息
上游原料
下游产品
DIPHTHERIA TOXIN生产厂家
- 公司名称：SIGMA
- 联系电话：--
- 电子邮件：
- 国家：瑞士
- 产品数：6913
- 优势度：91
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