ChemicalBook CAS数据库列表 D-赤式-C 18 - 二氢-D-神经鞘氨醇
D-赤式-C 18 - 二氢-D-神经鞘氨醇
- CAS号:764-22-7
- 英文名:D-erythro-C18-Dihydro-D-sphingosine
- 中文名:D-赤式-C 18 - 二氢-D-神经鞘氨醇
- CBNumber:CB42130435
- 分子式:C18H39NO2
- 分子量:301.51
- MOL File:764-22-7.mol
D-赤式-C 18 - 二氢-D-神经鞘氨醇化学性质
- 熔点 :70-72°C
- 沸点 :446.2±25.0 °C(Predicted)
- 密度 :0.927±0.06 g/cm3(Predicted)
- 储存条件 :-20°C
- 溶解度 :DMSO: soluble25mg/mL (warm)
- 酸度系数(pKa) :12.57±0.45(Predicted)
- 形态 :White to off-white solid.
- 颜色 :white
- 稳定性 :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
安全信息
- WGK Germany :3
D-赤式-C 18 - 二氢-D-神经鞘氨醇性质、用途与生产工艺
- 生物活性 D-Erythro-dihydrosphingosin 直接抑制细胞溶质中的磷脂酶 A2α (cPLA2α) 活性。
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靶点
Human Endogenous Metabolite
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体外研究
D-Erythro-dihydrosphingosine (D-erythro-DHS) significantly inhibits mastoparan-, but not Na 3 VO 4 -, stimulated arachidonic acid release in PC12 cells. D-Erythro-dihydrosphingosine at 100 AM slightly inhibits [ 3 H]Arachidonic acid release, and 5 μM Ionomycin alone stimulates the release significantly. In the presence of 5 μM Ionomycin, 100 μM C2-ceramide stimulates the release, but D-Erythro-dihydrosphingosine (100 μM) inhibits the release. D-Erythro-dihydrosphingosine inhibits arachidonic acid release in cells and/or cPLA 2 α activity.
D-赤式-C 18 - 二氢-D-神经鞘氨醇上下游产品信息
上游原料
下游产品
D-赤式-C 18 - 二氢-D-神经鞘氨醇生产厂家
- 公司名称：SYNCHEM-OHG
- 联系电话：+49 5662 408730
- 电子邮件：info@synchem.de
- 国家：德国
- 产品数：4705
- 优势度：70
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