理化性质 贮存 生物活性 靶点 体外研究 丝拉克肽 试剂级价格
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丝拉克肽

丝拉克肽,12279-41-3,结构式
丝拉克肽
  • CAS号:12279-41-3
  • 英文名:Seractide
  • 中文名:丝拉克肽
  • CBNumber:CB3318698
  • 分子式:C207H308N56O58S1
  • 分子量:4541.07
  • MOL File:12279-41-3.mol
丝拉克肽化学性质
  • 储存条件 :Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
  • 溶解度 :H2O: 1 mg/mL, clear, colorless
  • 形态 :Solid
  • 水溶解性 :Soluble to 1 mg/ml in water
  • 序列 :H-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-Gly-Lys-Lys-Arg-Arg-Pro-Val-Lys-Val-Tyr-Pro-Asn-Gly-Ala-Glu-Asp-Glu-Ser-Ala-Glu-Ala-Phe-Pro-Leu-Glu-Phe-OH
安全信息
  • 危险品标志 :Xn
  • 危险类别码 :20/21/22-40
  • 安全说明 :22-36
  • WGK Germany :3
  • RTECS号 :GM7900000
  • F :8-10

丝拉克肽性质、用途与生产工艺

  • 理化性质 类白色粉末,有特臭。
  • 贮存 储存温度:-20℃
  • 生物活性 Adrenocorticotropic Hormone (ACTH) (1-39), human 是一种黑皮质素受体 (melanocortin receptor) 激动剂。
  • 靶点

    Melanocortin receptor

  • 体外研究

    Adrenocorticotropic Hormone (ACTH) (1-39), human (ACTH 1-39), a member of the melanocortin family, stimulates production of CS by the adrenals, but melanocortin receptors are also found in the central nervous system (CNS) and on immune cells. ACTH 1-39 protects neurons in vitro from several apoptotic, excitotoxic and inflammation-related insults. The conditioned medium (CM) is prepared from untreated astroglia (AS) cultures and from AS cultures treated with 200 nM ACTH 1-39 for 24 h, washed to remove ACTH 1-39, then incubated for another 24 h in DMEM. In initial experiments, no difference is found in oligodendroglia (OL) viability in the presence of OL definedmediumwith 2% newborn calf serum (NCS) or AS CM (prepared in DMEM with no serum). After 24 h, OL death under each condition varies between 1 and 4%. Similar results for OL viability are obtained with microglia (MG) CM. In subsequent experiments, controls in each experiment consist of OL in defined medium with 2% NCS.

  • 参考质量标准 外观?白色粉末纯度(HPLC) ≥95.0%
    醋酸根含量5.0%~12.0%
    水分含量≤8.0%
    肽含量≥80.0%
  • 用途  可用于生产促肾上腺皮质激素(ACTH),助应素。在兽药生产上,可用于促黄体激素和促卵泡激素的生产。
丝拉克肽上下游产品信息
上游原料
下游产品
丝拉克肽 试剂级价格
  • 更新日期:2024/01/25
  • 产品编号:HY-P1211
  • 产品名称:丝拉克肽 Adrenocorticotropic Hormone (ACTH) (1-39), human
  • CAS编号:12279-41-3
  • 包装:1mg
  • 价格:2200元
  • 更新日期:2024/01/25
  • 产品编号:HY-P1211
  • 产品名称:丝拉克肽 Adrenocorticotropic Hormone (ACTH) (1-39), human
  • CAS编号:12279-41-3
  • 包装:5mg
  • 价格:5500元
丝拉克肽生产厂家
  • 公司名称:北京百灵威科技有限公司
  • 联系电话:010-82848833 400-666-7788
  • 电子邮件:jkinfo@jkchemical.com
  • 国家:中国
  • 产品数:96815
  • 优势度:76
  • 公司名称:吉尔生化(上海)有限公司
  • 联系电话:21-61263452 13641803416
  • 电子邮件:ymbetter@glbiochem.com
  • 国家:中国
  • 产品数:9981
  • 优势度:64
  • 公司名称:TargetMol中国(陶术生物)
  • 联系电话:021-33632979 15002134094
  • 电子邮件:marketing@targetmol.com
  • 国家:中国
  • 产品数:7934
  • 优势度:58
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