ChemicalBook CAS数据库列表 4'-甲氧基查耳酮
4'-甲氧基查耳酮
- CAS号:959-23-9
- 英文名:4'-METHOXYCHALCONE
- 中文名:4'-甲氧基查耳酮
- CBNumber:CB2374303
- 分子式:C16H14O2
- 分子量:238.28
- MOL File:959-23-9.mol
4'-甲氧基查耳酮化学性质
- 熔点 :101-103 °C(lit.)
- 沸点 :397.5±42.0 °C(Predicted)
- 密度 :1.114±0.06 g/cm3(Predicted)
- 形态 :Solid
- 颜色 :White to light yellow
- 水溶解性 :Soluble in dichloromethane and methanol. Insoluble in water.
- BRN :644640
- LogP :4.180 (est)
- CAS 数据库 :959-23-9(CAS DataBase Reference)
安全信息
4'-甲氧基查耳酮性质、用途与生产工艺
- 生物活性 4'-Methoxychalcone存在于柑橘属植物中，是一种查耳酮衍生物，具有多种药理活性，如抗肿瘤和消炎活性。
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靶点
PPARγ
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体外研究
4'-Methoxychalcone (5 μM; 8 days) markedly increases the mRNA expression of adipogenic genes during adipocyte differentiation, PPARγ, aP2, FAS, adiponectin and GluT 4. 4'-Methoxychalcone (5 μM; 8 days) reduces the upregulated mRNA expression of IL-6, PAI-1, and MCP-1 by TNF-α in preadipocyte 3T3-L1 cells. 4'-Methoxychalcone (5 μM; 0-8 days) causes an increase in PPARγ expression during differentiation, while C/EBPβ protein expression is relatively unaffected.
RT-PCR
Cell Line: Preadipocyte 3T3-L1 cells Concentration: 5 μM Incubation Time: 0 day; 2 days; 4 days; 6 days; 8 days Result: Increased the mRNA expression of all adipogenic genes, except GluT1 in adipocyte. Western Blot Analysis
Cell Line: Preadipocyte 3T3-L1 cells Concentration: 5 μM Incubation Time: 8 days Result: Increased PPARγ expression in adipocyte.
4'-甲氧基查耳酮上下游产品信息
上游原料
下游产品
4'-甲氧基查耳酮 试剂级价格
- 更新日期：2024/11/08
- 产品编号：B22158
- 产品名称：4’-甲氧基查耳酮, 97% 4'-Methoxychalcone, 97%
- CAS编号：959-23-9
- 包装：5g
- 价格：298元
- 更新日期：2024/11/08
- 产品编号：B22158
- 产品名称：4’-甲氧基查耳酮, 97% 4'-Methoxychalcone, 97%
- CAS编号：959-23-9
- 包装：25g
- 价格：736元
4'-甲氧基查耳酮生产厂家
- 公司名称：SIGMA
- 联系电话：--
- 电子邮件：
- 国家：瑞士
- 产品数：6896
- 优势度：91
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