ChemicalBook CAS数据库列表 7-二甲氧基-N-(4-苯氧基苯基)- 氨基喹唑啉
7-二甲氧基-N-(4-苯氧基苯基)- 氨基喹唑啉
- CAS号:179248-59-0
- 英文名:6,7-Dimethoxy-N-(4-phenoxyphenyl)-
- 中文名:7-二甲氧基-N-(4-苯氧基苯基)- 氨基喹唑啉
- CBNumber:CB22508388
- 分子式:C22H19N3O3
- 分子量:373.4
- MOL File:179248-59-0.mol
7-二甲氧基-N-(4-苯氧基苯基)- 氨基喹唑啉化学性质
- 储存条件 :2-8°C
- 溶解度 :DMSO: >10mg/mL
- 形态 :white powder
- 颜色 :White or off-white
- 稳定性 :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 week.
安全信息
- 危险品标志 :Xn
- 危险类别码 :22-36/37/38
- 安全说明 :26
- 危险品运输编号 :UN 3077 9 / PGIII
- WGK Germany :3
7-二甲氧基-N-(4-苯氧基苯基)- 氨基喹唑啉性质、用途与生产工艺
- 生物活性 Src Inhibitor 1是Src和Lck的竞争性抑制剂，IC50分别为44 nM和88 nM。它也能抑制Csk和Yes。
-
靶点
Target Value Src
(Cell-free assay)44 nM Lck
(Cell-free assay)88 nM -
体外研究
Src-I1 is competitive with both ATP and peptide binding sites of the kinase. The IC 50 values are 44 and 88 nM for Src and Lck, respectively. Src-I1, is found to be a potent inhibitor of Src (IC 50 =0.18 μM), but also inhibited other Src family members, such as Lck, Csk and Yes with similar potency to Src, and RIP2 (IC 50 =0.026 μM) with even greater potency. In addition, it inhibited CHK2 with similar potency to Src, and Aurora B with slightly lower potency.
7-二甲氧基-N-(4-苯氧基苯基)- 氨基喹唑啉上下游产品信息
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7-二甲氧基-N-(4-苯氧基苯基)- 氨基喹唑啉 试剂级价格
- 更新日期：2024/11/08
- 产品编号：HY-101053
- 产品名称：7-二甲氧基-N-(4-苯氧基苯基)- 氨基喹唑啉 Src Inhibitor 1
- CAS编号：179248-59-0
- 包装：2mg
- 价格：500元
- 更新日期：2024/11/08
- 产品编号：HY-101053
- 产品名称：7-二甲氧基-N-(4-苯氧基苯基)- 氨基喹唑啉 Src Inhibitor 1
- CAS编号：179248-59-0
- 包装：10mM * 1mLin DMSO
- 价格：575元
7-二甲氧基-N-(4-苯氧基苯基)- 氨基喹唑啉生产厂家
- 公司名称：TOCRIS-US
- 联系电话：--
- 电子邮件：customerservice@tocris.co.uk
- 国家：英国
- 产品数：5726
- 优势度：77
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