生物活性 靶点 体外研究 体内研究
ChemicalBook  CAS数据库列表  (GLY1,SER3·22,GLN4·34,THR6,ARG19,TYR21,ALA23·31,AIB32)-PANCREATIC POLYPEPTIDE (HUMAN)

(GLY1,SER3·22,GLN4·34,THR6,ARG19,TYR21,ALA23·31,AIB32)-PANCREATIC POLYPEPTIDE (HUMAN)

(GLY1,SER3·22,GLN4·34,THR6,ARG19,TYR21,ALA23·31,AIB32)-PANCREATIC POLYPEPTIDE (HUMAN),313988-89-5,结构式
(GLY1,SER3·22,GLN4·34,THR6,ARG19,TYR21,ALA23·31,AIB32)-PANCREATIC POLYPEPTIDE (HUMAN)
  • CAS号:313988-89-5
  • 英文名:(Gly1,Ser3·22,Gln4·34,Thr6,Arg19,Tyr21,Ala23·31,Aib32)-Pancreatic Polypeptide (human)
  • 中文名:(GLY1,SER3·22,GLN4·34,THR6,ARG19,TYR21,ALA23·31,AIB32)-PANCREATIC POLYPEPTIDE (HUMAN)
  • CBNumber:CB22476144
  • 分子式:C183H281N57O54S2
  • 分子量:4207.66874
  • MOL File:313988-89-5.mol
(GLY1,SER3·22,GLN4·34,THR6,ARG19,TYR21,ALA23·31,AIB32)-PANCREATIC POLYPEPTIDE (HUMAN)化学性质
  • 储存条件 :Store at -20°C
  • 溶解度 :Soluble to 1 mg/ml in 10% acetonitrile
  • 形态 :Powder
  • 颜色 :White to off-white

(GLY1,SER3·22,GLN4·34,THR6,ARG19,TYR21,ALA23·31,AIB32)-PANCREATIC POLYPEPTIDE (HUMAN)性质、用途与生产工艺

  • 生物活性 [cPP1-7,NPY19-23,Ala31,Aib32,Gln34]-hPancreatic Polypeptide 是一种有效的,选择性神经肽 YY5 受体激动剂,与 hY5 受体结合的 IC50 值为 0.24 nM。[cPP1-7,NPY19-23,Ala31,Aib32,Gln34]-hPancreatic Polypeptide 增加饮食摄入量。
  • 靶点

    hY 5 receptor

    0.24 nM (IC 50 )

    hY 1 receptor

    530 nM (IC 50 )

    hY 2 receptor

    >500 nM (IC 50 )

    hY 4 receptor

    51 nM (IC 50 )

  • 体外研究

    [cPP1-7,NPY19-23,Ala31,Aib32,Gln34]-hPancreatic Polypeptide has IC 50 s of 530 nM, >500 nM, 51 nM for binding to the hY 1 , hY 4 , hY 2 receptors.

  • 体内研究

    [cPP1-7,NPY19-23,Ala31,Aib32,Gln34]-hPancreatic Polypeptide (0.2, 2 nmol/rat) induces a high amount of food intake in a dose-dependent manner in adult male rats weighing 340-400 g.

(GLY1,SER3·22,GLN4·34,THR6,ARG19,TYR21,ALA23·31,AIB32)-PANCREATIC POLYPEPTIDE (HUMAN)上下游产品信息
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(GLY1,SER3·22,GLN4·34,THR6,ARG19,TYR21,ALA23·31,AIB32)-PANCREATIC POLYPEPTIDE (HUMAN)生产厂家
  • 公司名称:BOC Sciences
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  • 国家:美国
  • 产品数:0
  • 优势度:65
  • 公司名称:MedChemExpress
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  • 国家:美国
  • 产品数:6398
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