鸢尾黄素
- CAS号:548-77-6
- 英文名:Tectorigenin
- 中文名:鸢尾黄素
- CBNumber:CB11040716
- 分子式:C16H12O6
- 分子量:300.26
- MOL File:548-77-6.mol
- 熔点 :225-226°
- 沸点 :361.5°C (rough estimate)
- 密度 :1.512
- 折射率 :1.4600 (estimate)
- 储存条件 :Sealed in dry,2-8°C
- 溶解度 :DMSO : 150 mg/mL (499.57 mM; Need ultrasonic and warming)
- 形态 :powder to crystal
- 酸度系数(pKa) :6.49±0.20(Predicted)
- 颜色 :White to Orange to Green
- BRN :305601
- InChI :InChI=1S/C16H12O6/c1-21-16-11(18)6-12-13(15(16)20)14(19)10(7-22-12)8-2-4-9(17)5-3-8/h2-7,17-18,20H,1H3
- InChIKey :OBBCRPUNCUPUOS-UHFFFAOYSA-N
- SMILES :C1OC2=CC(O)=C(OC)C(O)=C2C(=O)C=1C1=CC=C(O)C=C1
- CAS 数据库 :548-77-6
- WGK Germany :3
- RTECS号 :NR2400000
- 海关编码 :2932.99.6100
鸢尾黄素性质、用途与生产工艺
- 生物活性 Tectorigenin 是一种植物异黄酮,最初是从葛根汤干燥的花中分离出来的。
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体外研究
Tectorigenin is a plant isoflavonoid originally isolated from the dried flower of Pueraria thomsonii Benth. Palmitic acid (PA)-stimulated ROS production is abolished by treatment with Tectorigenin for HUVECs in a dose-dependent manner (0.1, 1, 10 μM). Treatment with Tectorigenin attenuates enhanced IKKβ phosphorylation and effectively blocks NF-κB activation by inhibition of p65 phosphorylation at concentrations ranging from 0.1 to 10 μM. Tectorigenin treatment also effectively inhibits PA-augmented TNF-α and IL-6 production in a concentration dependent manner. The number of viable HepG2 cells treated by Tectorigenin decreases in a concentration- and time-dependent manner. When HepG2 cells are treated with Tectorigenin at 5, 10 and 20 mg/L for 24 h, the viability rate is 91%, 79% and 62%, respectively.
- 化学性质 淡黄色结晶,可溶于甲醇、乙醇、DMSO等有机溶剂,来源于植物射干的根茎。
- 用途 射干苷元具有抗病毒、抗炎、解热和镇痛的作用。
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用途
用于含量测定/鉴定/药理实验等。
药理药效:具有清热解毒、利咽消痰、散血消肿的功效
- 更新日期:2024/11/08
- 产品编号:T3729
- 产品名称:鸢尾苷 Tectorigenin
- CAS编号:548-77-6
- 包装:10mg
- 价格:270元
- 更新日期:2024/11/08
- 产品编号:T3729
- 产品名称:鸢尾苷 Tectorigenin
- CAS编号:548-77-6
- 包装:50mg
- 价格:990元
- 公司名称:TCI Chemicals (India) Pvt. Ltd.
- 联系电话:--
- 电子邮件:sales-in@tcichemicals.com
- 国家:印度
- 产品数:6768
- 优势度:58