851331-05-0
中文名称
YM-53403
英文名称
YM-53403
CAS
851331-05-0
分子式
C36H29N3O3S
分子量
583.7
MOL 文件
851331-05-0.mol
结构式
![851331-05-0 结构式](https://www.chemicalbook.com/CAS/20210305/GIF/851331-05-0.gif)
应用领域
用途一
YM-53403 is a respiratory syncytial virus (RSV) inhibitor. YM-53403 potently inhibited the replication of RSV strains belonging to both A and B subgroups, but not influenza A virus, measles virus, or herpes simplex virus type 1. A plaque reduction assay was used to determine the 50% effective concentration (EC(50)) value for YM-53403. The value, 0.20 microM, was about 100-fold more potent than ribavirin. YM-53403 is an attractive compound for the treatment of RSV infection because of its highly potent anti-RSV activity and the new mode of action, which differs from that of currently reported antiviral agents.