74885-72-6
基本信息
5-carboxyamidotryptamine maleate
5-Carboxamidotryptamine maleate salt hemiethanolate
物理化学性质
| 储存条件 | -20°C |
| 溶解度 | H2O：可溶，10mg/mL |
| 形态 | 粉末 |
| 颜色 | 白色至灰白色 |
| 水溶解性 | 溶于水至100mM |
| InChI | 1S/C11H13N3O.C4H4O4/c12-4-3-8-6-14-10-2-1-7(11(13)15)5-9(8)10;5-3(6)1-2-4(7)8/h1-2,5-6,14H,3-4,12H2,(H2,13,15);1-2H,(H,5,6)(H,7,8)/b;2-1- |
| InChIKey | PZQZSWAOVAMBQM-BTJKTKAUSA-N |
| SMILES | OC(=O)\C=C/C(O)=O.NCCc1c[nH]c2ccc(cc12)C(N)=O |
安全数据
| 危险性符号(GHS) |  GHS07 |
| 警示词 | 警告 |
| 危险性描述 | H315-H319-H335 |
| 防范说明 | P261-P264-P271-P280-P302+P352-P305+P351+P338 |
| 危险品标志 | Xi |
| 危险类别码 | 36/37/38 |
| 安全说明 | 26-36 |
| WGK Germany | 3 |
| 存储类别 | 11 - Combustible Solids |
| 危险性类别 | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
5-carboxyamidotryptamine maleate价格(试剂级)
| 报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
| 2026/09/15 | HY-100942 | 5-carboxyamidotryptamine maleate 5-Carboxamidotryptamine maleate | 74885-72-6 | 1 mg | 285元 |
| 2026/09/15 | HY-100942 | 5-carboxyamidotryptamine maleate 5-Carboxamidotryptamine maleate | 74885-72-6 | 5 mg | 688元 |
| 2026/09/15 | HY-100942 | 5-carboxyamidotryptamine maleate 5-Carboxamidotryptamine maleate | 74885-72-6 | 10 mM * 1 mL in DMSO | 756元 |
常见问题列表
|
5-HT 1A Receptor
|
5-HT 1B Receptor
|
5-HT 1D Receptor
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5-HT 5 Receptor
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5-HT 7 Receptor
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[
3
H]-5-Carboxamidotryptamine (5-CT) binding to 5-HT
1D
sites in bovine substantia nigra is rapid, reversible and saturable, displaying high affinity (K
d
= 0.38 nM) and low non-specific binding.
In bovine substantia nigra, [
3
H]-5-Carboxamidotryptamine (5-CT) labelled an equivalent number of binding sites to [
3
H]-5-Carboxamidotryptamine (403 and 362 fmol/mg protein, respectively) and binding is sensitive to guanine nucleotides.
Topical 5-Carboxamidotryptamine (0.01-1000 μM) to the exposed dura mater encephala produced decreases in diastolic blood pressure, variable changes in meningeal blood flow and increases in conductance (i.e. dilatation) in the middle meningeal artery of anesthetized Wistar rats (serotonin depletion and treated with 20 mg/kg corticosterone).