67384-25-2
中文名称
(5alpha,8alpha,9alpha)-5,8,9,10-tetrahydro-5,9-methanobenzocycloocten-8-ylammonium chloride
英文名称
(5alpha,8alpha,9alpha)-5,8,9,10-tetrahydro-5,9-methanobenzocycloocten-8-ylammonium chloride
CAS
67384-25-2
分子式
C13H16ClN
分子量
221.726
MOL 文件
67384-25-2.mol
结构式
基本信息
中文别名
化合物 T28266
英文别名
Org-6906 free
(5alpha,8alpha,9alpha)-5,8,9,10-tetrahydro-5,9-methanobenzocycloocten-8-ylammonium chloride
(5alpha,8alpha,9alpha)-5,8,9,10-tetrahydro-5,9-methanobenzocycloocten-8-ylammonium chloride
应用领域
用途一
Org-6906 is a dual of monoamine uptake inhibitor and α2 adrenoceptor antagonist potentially for the treatment. Org-6906 facilitated potassium-stimulated release of noradrenaline from slices of cortex, displaced [3H]rauwolscine and [3H]dihydroergocryptine from their binding sites but only weakly blocked alpha 1-adrenoceptors. The alpha 2-adrenolytic properties were also apparent in behavioural interaction models. The compound antagonized the sleep-inducing effects of clonidine in chicks and mice and it antagonized the mydriasis induced by clonidine in the rat.