607736-84-5
物理化学性质
| 储存条件 | -20°C储存 |
| 溶解度 | 溶于二甲基亚砜 |
| 形态 | Solid |
| 颜色 | Light yellow to yellow |
607736-84-5价格(试剂级)
| 报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
| 2026/09/15 | HY-U00084 | 607736-84-5 SUN 1334H | 607736-84-5 | 1mg | 1485元 |
| 2026/09/15 | HY-U00084 | 607736-84-5 SUN 1334H | 607736-84-5 | 5 mg | 3714元 |
| 2026/09/15 | HY-U00084 | 607736-84-5 SUN 1334H | 607736-84-5 | 10 mM * 1 mL in Water | 3999元 |
常见问题列表
Ki: 9.7 nM (H1 receptor)
SUN-1334H causes potent inhibition of histamine induced contractions of isolated guinea-pig ileum with an IC 50 (half the maximal inhibitory concentration) of 0.198 μM. In CHO-K1/hERG cells, SUN-1334H does not modulate hERG K + -currents at concentrations as high as 100 μM. SUN-1334H, cetirizine and hydroxyzine cause comparable inhibition of NLF leukocytes, IL-4 and total protein concentrations.
SUN-1334H potently inhibits histamine-induced bronchospasm over 24 hours following oral administration and completely suppresses histamine-induced skin wheal in beagle dogs and ovalbumin-induced rhinitis in guinea pigs. In skin allergy models, SUN-1334H shows potent reduction of passive and active cutaneous anaphylactic reactions. In central nervous system side effects models, SUN-1334H, desloratadine and fexofenadine are devoid of any significant effects.