537-46-2
中文名称
晶体,晶粒,结晶
英文名称
D-METHAMPHETAMINE
CAS
537-46-2
分子式
C10H15N
分子量
149.23
MOL 文件
537-46-2.mol
结构式
基本信息
中文别名
冰,结冰
甲苯丙胺
去氧麻黄碱
晶体,晶粒,结晶
S(+)-甲基苯丙胺
N,α-二甲基苯乙胺
甲苯丙胺
去氧麻黄碱
晶体,晶粒,结晶
S(+)-甲基苯丙胺
N,α-二甲基苯乙胺
英文别名
anadrex
crystal
Norodin
Dexafed
stimulex
pervertin
NSC 25115
methedrine
Metamfetamine
deoxy-ephedrin
crystal
Norodin
Dexafed
stimulex
pervertin
NSC 25115
methedrine
Metamfetamine
deoxy-ephedrin
所属类别
原料药：其它神经系统用药
物理化学性质
| 熔点 | 143°C (estimate) |
| 沸点 | 230.33°C (estimate) |
| 密度 | 0.9285 (estimate) |
| 折射率 | 1.5105 (estimate) |
| 闪点 | 9℃ |
| 储存条件 | 2-8°C |
| 酸度系数(pKa) | 10.38±0.10(Predicted) |
安全数据
| 危险性符号(GHS) |    GHS02,GHS06,GHS08 |
| 警示词 | 危险 |
| 危险性描述 | H225-H301+H311+H331-H370 |
| 防范说明 | P210-P260-P280-P301+P310-P311 |
| 危险品标志 | F,T |
| 危险类别码 | 11-23/24/25-39/23/24/25 |
| 安全说明 | 16-36/37-45 |
| 危险品运输编号 | 1851 |
| WGK Germany | 1 |
| REACH 注册登记 | Active |
| 危险等级 | 6.1(b) |
| 包装类别 | III |
| 毒害物质数据 | 537-46-2(Hazardous Substances Data) |
| 毒性 | A widely abused drug; a sympathomimetic and central stimulant that has been used clinically as an anorectic agent. The use of methamphetamine and related drugs in treating obesity is, however, now generally discredited. It may cause elevation of blood pressure, palpitation, and tachycardia, as well as various CNS effects, including psychotic effects at higher doses. Chronic use of methamphetamine and related compounds, especially at high doses as often occurs with drug abuse, can cause a condition often indistinguishable from schizophrenia. Abrupt withdrawal may cause fatigue, depression, and sleep changes. Methamphetamine is an indirect-acting adrenergic and dopamine agonist that acts principally to release endogenous catecholamines, thereby increasing their synaptic availability. Many of its actions can be blocked by adrenergic and dopamine antagonists. The i.p. LD50 in mice is 70 mg/kg. |
应用领域
用途1
食欲抑制剂司来吉克的中间体。