505-44-2
基本信息
3-甲基亚磺酰丙基异硫氰酸酯
lberin
NSC 321801
IBERIN(RG)
3-methylsulphinylpropylisothiocyanate
3-(Methylsulfinyl)propyl isothiocyanate
Methyl(3-isothiocyanatopropyl) sulfoxide
3-methylsulfinylpropylimino(thioxo)methane
1-isothiocyanato-3-(methylsulfinyl)propane
1-ISOTHIOCYANATO-3-(METHYLSULPHINYL)-PROPANE
物理化学性质
| 沸点 | 240.37°C (rough estimate) |
| 密度 | 1.142 (estimate) |
| 折射率 | 1.5237 (estimate) |
| 储存条件 | Hygroscopic, Refrigerator, under inert atmosphere |
| 溶解度 | 可溶于氯仿（少许）、甲醇（少许） |
| 形态 | Oil |
| 颜色 | 无色 |
| 稳定性 | 湿气敏感 |
| InChIKey | LELAOEBVZLPXAZ-UHFFFAOYSA-N |
| SMILES | [S](=O)(CCCN=C=S)C |
安全数据
| 危险性符号(GHS) |    GHS07,GHS08,GHS05 |
| 警示词 | 危险 |
| 危险性描述 | H332-H334-H318-H302-H312-H315-H335 |
| 防范说明 | P264-P270-P301+P312-P330-P501-P261-P271-P304+P340-P312-P280-P302+P352-P312-P322-P363-P501-P264-P280-P302+P352-P321-P332+P313-P362-P280-P305+P351+P338-P310-P261-P285-P304+P341-P342+P311-P501 |
| WGK Germany | WGK 3 |
| 存储类别 | 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects |
| 危险性类别 | Acute Tox. 3 Dermal Acute Tox. 3 Inhalation Acute Tox. 3 Oral Aquatic Acute 1 Aquatic Chronic 1 Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
3-甲基亚磺酰丙基异硫氰酸酯价格(试剂级)
| 报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
| 2026/09/15 | HY-101413 | 3-甲基亚磺酰丙基异硫氰酸酯 Iberin | 505-44-2 | 1mg(61.25mM * 100μL in Ethanol) | 750元 |
| 2026/09/15 | HY-101413 | 3-甲基亚磺酰丙基异硫氰酸酯 Iberin | 505-44-2 | 5 mg (61.25 mM * 500 μL in Ethanol) | 1880元 |
| 2026/09/15 | HY-101413 | 3-甲基亚磺酰丙基异硫氰酸酯 Iberin | 505-44-2 | 10 mg (61.25 mM * 1 mL in Ethanol) | 3000元 |
常见问题列表
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Human Endogenous Metabolite
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Iberin inhibits the growth of neuroblastoma cells in a dose- and time-dependent manner. The iberin-induced cell cycle arrest in neuroblastoma cells is associated with inhibition of expression of cyclin-dependent kinase Cdk2, Cdk4, and Cdk6 proteins. There is an increase in apoptotic cell death in iberin treated cells as compared with control cells. The iberin-induced apoptosis is found to be associated with activation of caspase-9, caspase-3, and PARP. Iberin inhibits growth of human glioblastoma cells in cell proliferation assays, enhances cytotoxicity, and induces apoptosis by activation of caspase-3 and caspase-9.
Iberin is tested in an in vivo foreign-body infection mouse model, and the results show no significantly difference in bacterial clearance between treated and nontreated miced. Iberin increases tissue levels of the phase II detoxification enzymes quinone reductase and glutathione S-transferase in a variety of rat tissues.