4551-00-2
基本信息
SOS1 inhibitor 1
9H-Fluorene,9-[3-(2-nitrophenyl)-2-propen-1-ylidene]-
物理化学性质
| 熔点 | 186 °C |
| 沸点 | 569.6±49.0 °C(Predicted) |
| 密度 | 1.321±0.06 g/cm3(Predicted) |
| 储存条件 | Store at -20°C,unstable in solution, ready to use. |
| 溶解度 | DMSO: 12.5 mg/mL (38.42 mM) |
| 形态 | Solid |
| 颜色 | Light yellow to yellow |
9H-Fluorene,9-[3-(2-nitrophenyl)-2-propen-1-ylidene]-价格(试剂级)
| 报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
| 2025/05/22 | HY-101796 | 9H-Fluorene,9-[3-(2-nitrophenyl)-2-propen-1-ylidene]- NSC-70220 | 4551-00-2 | 5mg | 900元 |
| 2025/05/22 | HY-101796 | 9H-Fluorene,9-[3-(2-nitrophenyl)-2-propen-1-ylidene]- NSC-70220 | 4551-00-2 | 10mg | 1500元 |
| 2025/05/22 | HY-101796 | 9H-Fluorene,9-[3-(2-nitrophenyl)-2-propen-1-ylidene]- NSC-70220 | 4551-00-2 | 25mg | 3000元 |
常见问题列表
SOS1.
The growth inhibitory rate (IR)=(average OD value in the control group-average OD value in the treatment group)/average OD value in the control group×100% are compared. Treatments with NSC-70220 at 40 μM and NSC-658497 at 30 μM result in growth inhibitory rate of 29% and 8% respectively. The combination treatment results in growth inhibitory rate of 54%, showing the synergistic effect of NSC-70220 and NSC-658497 on cell growth inhibition. It is showed that the treatment with NSC-658497 at 40 μM for 2 hours alone or in combìnation with the treatment with 40 μM of NSC-70220 overnight resulted in lower expression levels of P-AKT and P-ERK. The treatment wlth 40 μM of NSC-70220 overnight resulted in lower expression levels of P-ERK.