41733-55-5
基本信息
FuroseMide (sodiuM)
Sodium 5-(aminosulfonyl)-4-chloro-2-(furan-2-ylmethyl)anthranilate
sodium 5-(aminosulphonyl)-4-chloro-2-(furan-2-ylmethyl)anthranilate
5-(Aminosulfonyl)-4-chloro-2-[(2-furanylmethyl)amino]benzoic acid sodium salt
物理化学性质
| 储存条件 | -20°C储存 |
| 溶解度 | DMSO: ≥ 150 mg/mL (425.25 mM) |
| 形态 | Solid |
| 颜色 | White to off-white |
安全数据
| 危险性符号(GHS) |  GHS08 |
| 警示词 | 警告 |
| 危险性描述 | H341-H412-H361-H362 |
| 防范说明 | P273-P501-P201-P202-P281-P308+P313-P405-P501-P201-P260-P263-P264-P270-P308+P313-P201-P202-P281-P308+P313-P405-P501 |
呋塞米钠价格(试剂级)
| 报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
| 2024/04/30 | HY-B0135A | 呋塞米钠 Furosemide sodium | 41733-55-5 | 500mg | 900元 |
| 2024/04/30 | HY-B0135A | 呋塞米钠 Furosemide sodium | 41733-55-5 | 10mM * 1mLin DMSO | 990元 |
| 2024/04/30 | HY-B0135A | 呋塞米钠 Furosemide sodium | 41733-55-5 | 1g | 1500元 |
常见问题列表
IC50: NKCC1 and NKCC2IC50: GABA A receptors
Furosemide sodium (500 µM; 72-96 hours) significantly changes the proliferation rates in MKN45 cells (the poorly differentiated human gastric adenocarcinoma cell line). however, it has no effects on MKN28 cells (the moderately differentiated human gastric adenocarcinoma cell line). The growth rate of MKN45 cells is larger than that of MKN28 cells.Furosemide sodium (10 µM, 30 µM, 100 µM; 45 min exposure)significantly decreases cation channel activity and [Ca(2+)](i) in human erythrocytes drawn from healthy individuals. Tert-butylhydroperoxide similarly enhances the non-selective cation channels activity, increases [Ca(2+)](i) and triggered cell membrane scrambling, however, the effects is significantly blunted by Furosemide sodium again.
Furosemide sodium (intraperitoneal injection; 100 mg/kg; single dose) is injected after kanamycin (KM) (1000 mg/kg) to creat a deaf mouse model in C57BL/6 mouse. After injection, hearing loss and cochlear hair cell damage are evaluated on day 1, day 2 and day 3, respectively. The hearing is markedly deteriorated even from the next day (Day-1 group), OHCs (outer hair cell) morphology of apical, middle and basal turns are disorganized in mice on day3.