220386-56-1
中文名称
化合物 T29073
英文名称
UR-2922
CAS
220386-56-1
分子式
C25H25N7O6
分子量
519.52
MOL 文件
220386-56-1.mol
结构式
应用领域
用途一
UR-2922 is a new generation oral platelet GPIIb/IIIa antagonist. UR-2922 is the active form of the prodrug UR-3216. UR-2922 possessed a high affinity for the human platelet receptor (K(d) <1 nM) with a slow dissociation rate (k(off)= 90 min) in vitro. UR-2922 induced no ligand-induced binding sites (LIBS) expression or prothrombotic activity in human platelets, distinctly different from orbofiban and other small molecule antagonists.