21306-65-0
基本信息
NPD-123
Triphenyl compound A
S-Methyl-S-(4-benzyloxy-phenyl)-N-(p-toluolsulfonyl)-sulfimid
S-[4-(Benzyloxy)phenyl]-S-methyl-N-(p-tolylsulfonyl)-sulfilimine
S-[p-(Benzyloxy)phenyl]-S-methyl-N-(p-tolylsulfonyl)-sulfilimine
N-{[4-(Benzyloxy)phenyl](methyl)-γ4-sulfanylidene}-4-methylbenzenesulfonamide
Benzenesulfonamide, 4-methyl-N-[methyl[4-(phenylmethoxy)phenyl]-λ4-sulfanylidene]-
物理化学性质
| 沸点 | 587.6±60.0 °C(Predicted) |
| 密度 | 1.22±0.1 g/cm3(Predicted) |
| 储存条件 | 2-8°C |
| 溶解度 | 二甲基亚砜：>30mg/mL |
| 形态 | 白色粉末 |
| 颜色 | 白色 |
| InChI | 1S/C21H21NO3S2/c1-17-8-14-21(15-9-17)27(23,24)22-26(2)20-12-10-19(11-13-20)25-16-18-6-4-3-5-7-18/h3-15H,16H2,1-2H3 |
| InChIKey | IMUPOWQOXOCVBN-UHFFFAOYSA-N |
| SMILES | Cc1ccc(cc1)S(=O)(=O)N=S(C)c2ccc(OCc3ccccc3)cc2 |
安全数据
| WGK Germany | 3 |
| 存储类别 | 11 - Combustible Solids |
S-[4-(苄氧基)苯基]-S-甲基-N-(对甲苯基磺酰基)-硫亚胺价格(试剂级)
| 报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
| 2026/09/15 | HY-14454 | S-[4-(苄氧基)苯基]-S-甲基-N-(对甲苯基磺酰基)-硫亚胺 TPh A | 21306-65-0 | 5mg | 1000元 |
| 2026/09/15 | HY-14454 | S-[4-(苄氧基)苯基]-S-甲基-N-(对甲苯基磺酰基)-硫亚胺 TPh A | 21306-65-0 | 10 mM * 1 mLin DMSO | 1100元 |
| 2026/09/15 | HY-14454 | S-[4-(苄氧基)苯基]-S-甲基-N-(对甲苯基磺酰基)-硫亚胺 TPh A | 21306-65-0 | 10mg | 1700元 |
常见问题列表
The Pirin is a nuclear protein with the nuclear factor I/CCAAT box transcription factor (NFI/CTF). Pirin proteins are highly conserved between mammals, plants, fungi, and prokaryotic organisms and are considered to belong to the cupin superfamily.TPh A (20 μM; 5 hours) reduces the amount of pirin-bound Bcl3 and inhibits the interaction between pirin and Bcl3 in HEK293T cells in a glutathione S-transferase (GST) pulldown assay (HEK293T cells are transfected with vectors that encoded bcl3-Myc and pirin-His6 for 43 h of transfection).TPh A (0-100 μM; 48 hours) does not exert any potent cytotoxic activity against many human cancer cell lines, it against MCF7, MDA-MB231, HeLa, DU145, HepG2, A549, HT1080, WM266-4, and SK-MEL-28 cells with IC 50 values >50 μM, and exhibits IC 50 values of 27 μM, 20 μM and 26 μM for PC3 HL60 and HT29 cells, respectively.TPhA (0-50 μM; 48 hours) inhibits cell migration in WM266-4 cells, SK-MEL-28 cell in a concentration-dependent manner.
Cell Viability Assay
| Cell Line: | MCF7, MDA-MB231, HeLa, DU145, HepG2, A549, HT1080, WM266-4, and SK-MEL-28 cells |
| Concentration: | 0-100 μM |
| Incubation Time: | 48 hours |
| Result: | Did not exert any potent cytotoxic activity against many human cancer cell lines. |