2083621-91-2

MBM-17S s a potent NIMA-related kinase 2 (Nek2) inhibitor. MBM-17S effectively inhibits the proliferation of cancer cells by inducing cell cycle arrest and apoptosis. MBM-17S shows antitumor activities, and no obvious toxicity to mice.

MBM-17S 是有效的 NIMA-related kinase 2 (Nek2) 抑制剂，IC50 值为 3 nM，通过诱导细胞周期停滞和凋亡 (apoptosis)，抑制癌细胞的增殖，具有抗肿瘤活性，且对小鼠没有明显的毒性。