2064338-33-4
中文名称
化合物 DELGOCITINIB ETOH
英文名称
1,6-Diazaspiro[3.4]octane-1-propanenitrile, 3-methyl-β-oxo-6-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-, compd. with ethanol (1:1), (3S,4R)-
CAS
2064338-33-4
分子式
C18H24N6O2
分子量
356.43
MOL 文件
2064338-33-4.mol
结构式
基本信息
中文别名
化合物 DELGOCITINIB ETOH
英文别名
1,6-Diazaspiro[3.4]octane-1-propanenitrile, 3-methyl-β-oxo-6-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-, compd. with ethanol (1:1), (3S,4R)-
应用领域
用途一
Delgocitinib, also known as LEO-124249 and JTE052, is a potent and selective JAK inhibitor. JTE-052 reduces skin inflammation and ameliorates chronic dermatitis in rodent models: Comparison with conventional therapeutic agents. JTE-052 regulates contact hypersensitivity by downmodulating T cell activation and differentiation.